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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
The dynamins are a family of 100 kDa GTPases transcribed from at least three separate genes. At least four mRNA splice variants for each dynamin have been described. Dynamins contain several conserved regions including the conserved, amino-terminal GTPase domain, a centrally located membrane-binding plekstrin homology domain (PHD), and a coiled-coil region located in front of a proline-rich domain (PRD). The PRD is thought to mediate interactions between dynamin and numerous other cellular proteins. Dynamin I is expressed exclusively in neurons, dynamin II is ubiquitously expressed, and dynamin III is thought to be restricted to expression in the brain, testis, heart, and lung. The dynamins participate in the cellular process of clathrin-mediated and fluid-phase endocytosis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Dyna III; Dynamin III; Dynamin, testicular; Dynamin-3; T-dynamin; testicular dynamin
基因别名: 9630020E24Rik; AW061159; B230343F03Rik; C530045C17; DNM3; Dyn3; dynamin-2; KIAA0820; mKIAA0820
UniProt ID: (Mouse) Q8BZ98, (Rat) Q08877
Entrez Gene ID: (Mouse) 103967, (Rat) 171574