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Invitrogen
EHD1 Recombinant Rabbit Monoclonal Antibody (23GB5280)
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图: 1 / 3
EHD1 Antibody (MA5-52831) in ICC/IF
Immunocytochemistry analysis of EHD1 in C2C12 cells. Sample was incubated with EHD1 monoclonal (Product # MA5-52830) antibody at a dilution of 1:1,000, followed by DAPI and Alexa Fluor 647. Protein abundance based on laser intensity and smart gain: Medium. Scale bar: 20 μm.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA5-52831
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293F
分类
Recombinant Monoclonal
类型
Antibody
克隆号
23GB5280
抗原
A synthesized peptide derived from human EHD1 (1-45AA).
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
EHD1 acts in early endocytic membrane fusion and membrane trafficking of recycling endosomes. EHD1 also plays a role in myoblast fusion and is recruited to endosomal membranes upon nerve growth factor stimulation, indirectly regulates neurite outgrowth. Further, EHD1 belongs to a highly conserved gene family encoding EPS15 homology (EH) domain-containing proteins. The protein-binding EH domain was first noted in EPS15, a substrate for the epidermal growth factor receptor. The EH domain has been shown to be an important motif in proteins involved in protein-protein interactions and in intracellular sorting. The EHD1 protein is thought to play a role in the endocytosis of IGF1 receptors. Alternatively spliced transcript variants have been found for the EHD1 gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: EH domain-containing protein 1; hPAST1; mPAST1; PAST homolog 1; Testilin
基因别名: AA409636; CDABP0131; EHD1; PAST; PAST1; RGD1306960; RME-1
UniProt ID: (Mouse) Q9WVK4, (Rat) Q641Z6
Entrez Gene ID: (Mouse) 13660, (Rat) 293692
intracellular protein transport
endocytosis
positive regulation of cholesterol storage
endosomal transport
neuron projection development
endocytic recycling
low-density lipoprotein particle clearance
cholesterol homeostasis
protein homooligomerization
positive regulation of myoblast fusion
cellular response to nerve growth factor stimulus
positive regulation of endocytic recycling
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