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Cdc42 Recombinant Rabbit Monoclonal Antibody (23GB740)

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Cdc42 Recombinant Rabbit Monoclonal Antibody (23GB740)

产品信息

MA5-53268

应用
建议稀释比
已发表文章

免疫印迹 (WB)

1:1,000-1:5,000
-

免疫细胞化学 (ICC/IF)

1:100-1:1,000
-

流式细胞分析 (Flow)

1:200-1:2,000
-
产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

Expression System

HEK293F

分类

Recombinant Monoclonal

类型

Antibody

克隆号

23GB740

抗原

A synthetic peptide of human CDC42 (50-191AA).
3D表位/免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1.5 mg/mL

规格

150 µg

纯化类型

Affinity chromatography

保存液

PBS, pH 7.4, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Ambient (domestic); Wet ice (international)

RRID

AB_3247741

靶标信息

Rac1 is a GTPase which belongs to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases. Two transcript variants encoding different isoforms have been found for the Rac1 gene.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: Cell division control protein 42 homolog; cell division cycle 42 (GTP binding protein); cell division cycle 42 homolog; G25K GTP-binding protein; GTP-binding protein; RP1-224A6.5

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基因别名: AI747189; AU018915; CDC42

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UniProt ID: (Rat) Q8CFN2, (Mouse) P60766

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Entrez Gene ID: (Rat) 64465, (Mouse) 12540

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功能
GTPase activity protein binding GTP binding protein kinase binding GTP-dependent protein binding mitogen-activated protein kinase kinase kinase binding thioesterase binding apolipoprotein A-I receptor binding identical protein binding nucleotide binding small GTPase
参与通路
positive regulation of protein phosphorylation sprouting angiogenesis cardiac conduction system development keratinocyte development endocytosis actin filament organization Golgi organization regulation of mitotic nuclear division nuclear migration small GTPase mediated signal transduction metabolic process response to glucose positive regulation of gene expression negative regulation of gene expression single organismal cell-cell adhesion regulation of exocytosis substantia nigra development establishment of cell polarity actin cytoskeleton organization hair follicle morphogenesis positive regulation of pseudopodium assembly negative regulation of protein complex assembly keratinization regulation of protein stability positive regulation of cytokinesis positive regulation of peptidyl-serine phosphorylation adherens junction organization cellular protein localization establishment or maintenance of apical/basal cell polarity multicellular organism growth dendritic cell migration regulation of protein catabolic process positive regulation of catalytic activity positive regulation of MAPK cascade regulation of protein heterodimerization activity positive regulation of neuron apoptotic process positive regulation of phosphatidylinositol 3-kinase activity positive regulation of DNA replication regulation of protein kinase activity positive regulation of JNK cascade filopodium assembly neuron fate determination epidermis morphogenesis actin filament bundle assembly regulation of protein metabolic process regulation of filopodium assembly nucleus localization establishment of Golgi localization positive regulation of synapse structural plasticity regulation of attachment of spindle microtubules to kinetochore heart contraction canonical Wnt signaling pathway submandibular salivary gland formation epithelial-mesenchymal cell signaling hair follicle placode formation positive regulation of hair follicle cell proliferation organelle transport along microtubule actin filament branching epithelial cell-cell adhesion positive regulation of intracellular protein transport positive regulation of substrate adhesion-dependent cell spreading establishment or maintenance of cell polarity Rho protein signal transduction nervous system development endosomal transport cell differentiation
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