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Invitrogen
AKR1C1/AKR1C2 Recombinant Rabbit Monoclonal Antibody (23GB3175)
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图: 1 / 4
AKR1C1/AKR1C2 Antibody (MA5-53602) in ICC/IF
Immunocytochemistry analysis of AKR1C1/AKR1C2 in HeLa cells. Nuclei were stained blue with DAPI; AKR1C1/AKR1C2 recombinant monoclonal antibody (Product # MA5-53602) with a dilution of 1:1,000 was stained magenta with Alexa Fluor 647. Images were taken using Leica stellaris 5. Protein abundance based on laser Intensity and smart gain: High. Scale bar: 20 μm.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA5-53602
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293F
分类
Recombinant Monoclonal
类型
Antibody
克隆号
23GB3175
抗原
A synthetic peptide of human AKR1C1/AKR1C2 (50-101AA).
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.54 mg/mL
规格
54 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols using NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme binds bile acid with high affinity, and shows minimal 3-alpha-hydroxysteroid dehydrogenase activity. And this gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. Three transcript variants encoding two different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 20-alpha-HSD; 20alpha-hydroxysteroid dehydrogenase; 3-alpha-HSD3; 3beta-hydroxysteroid 3-dehydrogenase; Aldo-keto reductase family 1 member C1; Aldo-keto reductase family 1 member C2; Chlordecone reductase homolog HAKRC; Chlordecone reductase homolog HAKRD; DD-2; DD/BABP; DD1; Dihydrodiol dehydrogenase 1; Dihydrodiol dehydrogenase 2; Dihydrodiol dehydrogenase/bile acid-binding protein; HBAB; High-affinity hepatic bile acid-binding protein; Type III 3-alpha-hydroxysteroid dehydrogenase
基因别名: AKR1C1; AKR1C2; DDH; DDH1; DDH2
Entrez Gene ID: (Human) 1645, (Human) 1646
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