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Invitrogen
Ganglioside GD2 (Lorukafusp Alfa Biosimilar) Recombinant Human Monoclonal Antibody
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Product Details
MA5-54931
Product Specifications
Species Reactivity
Human
Host/Isotype
Human
/ IgG1, kappa
Expression System
CHO cells
Class
Recombinant Monoclonal
Type
Antibody
Immunogen
Ganglioside GD2
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A/G
Storage buffer
PBS
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
RRID
Product Specific Information
Compatible with Direct ELISA
Target Information
Ganglioside GD2 is a disialoganglioside (glycosphingolipid) expressed on the outer surface of the plasma membrane. It is highly expressed in tumors of neuroectodermal origin, including neuroblastoma, melanoma, osteosarcoma, and small cell lung cancer, while showing limited distribution in normal tissues, primarily in peripheral nerves and the central nervous system. GD2 plays roles in cell adhesion, migration, and signal transduction. Because of its high tumor expression and restricted normal tissue distribution, GD2 is an established target for antibody-based immunotherapies, particularly in high-risk neuroblastoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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