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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen Sequence: IWYHGAISRG DAENLLRLCK ECSYLVRNSQ TSKHDYSLSL RSNQGFMHMK LAKTKEKYVL GQNSPPFDSV PEVIHYYTTR KLPIKGAEHL SLLYPVAVRT L
The SH2 (Src Homology 2) domain is a structurally conserved motif that contains two alpha helices and seven beta strands and is found in a variety of proteins that are involved in signal transduction throughout the cell. Specifically, the SH2 domain targets SH2 domain-containing proteins to tyrosinephosphorylated sites, an event that can trigger a protein-protein interaction cascade which may ultimately effect gene expression and cellular function. Shb (SH2 domain-containing adapter protein b), Shd (SH2 domain-containing adapter protein d), She (SH2 domain-containing adapter protein e) and Shf(SH2 domain-containing adapter protein f) are SH2 domain-containing proteins that play various roles throughout the cell.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: SH2 domain-containing adapter protein B; Src homology 2 domain containing adaptor protein B
基因别名: BC028832; RGD1565350; SHB
UniProt ID: (Mouse) Q6PD21
Entrez Gene ID: (Rat) 362513, (Mouse) 230126