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Invitrogen
CHD4 Recombinant Rabbit Monoclonal Antibody (0M3R5)
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CHD4 Antibody (MA5-55408) in IHC (P)
Immunohistochemistry analysis of paraffin-embedded Human spleen using CHD4 Recombinant Monoclonal Antibody (Product # MA5-55408) at a dilution of 1:200 (40x lens). High pressure antigen retrieval performed with 0.01M Citrate Buffer (pH 6. 0) prior to IHC staining.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA5-55408
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
0M3R5
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 1520-1700 of human CHD4.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1.22 mg/mL
规格
122 µg
纯化类型
Protein A
保存液
PBS, pH 7.3, with 0.05% BSA, 50% glycerol
内含物
0.05% ProClin 300
保存条件
-20°C, Avoid Freeze/Thaw Cycles
RRID
产品详细信息
Immunogen Sequence: ELAEVEENKK MSQPGSPSPK TPTPSTPGDT QPNTPAPVPP AEDGIKIEEN SLKEEESIEG EKEVKSTAPE TAIECTQAPA PASEDEKVVV EPPEGEEKVE KAEVKERTEE PMETEPKGAA DVEKVEEKSA IDLTPIVVED KEEKKEEEEK KEVMLQNGET PKDLNDEKQK KNIKQRFMFN I
靶标信息
The product of this gene belongs to the SNF2/RAD54 helicase family. It represents the main component of the nucleosome remodeling and deacetylase complex and plays an important role in epigenetic transcriptional repression. Patients with dermatomyositis develop antibodies against this protein.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
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生物信息学
蛋白别名: ATP-dependent chromatin remodeler CHD4; CHD-4; Chromo domain-containing protein 4; chromodomain-helicase-DNA-binding protein 4; Mi-2 autoantigen; Mi-2 autoantigen 218 kDa protein; Mi-2 beta; Mi2-beta; MI2B
基因别名: 9530019N15Rik; AA617397; BC005710; CHD4; D6Ertd380e; Mi-2; Mi-2beta; mKIAA4075
UniProt ID: (Mouse) Q6PDQ2
Entrez Gene ID: (Mouse) 107932, (Rat) 117535
nucleotide binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II distal enhancer sequence-specific DNA binding
RNA polymerase II repressing transcription factor binding
nucleic acid binding
DNA binding
helicase activity
protein binding
ATP binding
microtubule binding
ATP-dependent helicase activity
transcription factor binding
zinc ion binding
hydrolase activity
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
nucleosomal DNA binding
metal ion binding
molecular_function
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