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Invitrogen
GPRC5B Recombinant Rabbit Monoclonal Antibody (8Y9J4)
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GPRC5B Antibody (MA5-55461) in WB
Western Blot analysis of various lysates using GPRC5B Recombinant Monoclonal Antibody (Product # MA5-55461) at 1:500 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) at 1:10,000 dilution. Lysates/proteins: 25 μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA5-55461
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
8Y9J4
抗原
A synthetic peptide corresponding to a sequence within amino acids 304-403 of human GPRC5B.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.5 mg/mL
规格
50 µg
纯化类型
Protein A
保存液
PBS, pH 7.3, with 50% glycerol, 0.05% BSA
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
RRID
产品详细信息
Immunogen Sequence: TPNYFDTSQP RMRETAFEED VQLPRAYMEN KAFSMDEHNA ALRTAGFPNG SLGKRPSGSL GKRPSAPFRS NVYQPTEMAV VLNGGTIPTA PPSHTGRHLW
靶标信息
This gene encodes a member of the type 3 G protein-coupled receptor family. Members of this superfamily are characterized by a signature 7-transmembrane domain motif. The encoded protein may modulate insulin secretion and increased protein expression is associated with type 2 diabetes. Alternative splicing results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: A-69G12.1; G protein-coupled receptor, family C, group 5, member B; G-protein coupled receptor family C group 5 member B; hypothetical protein, clone 2-63; RAIG-2; Retinoic acid-induced gene 2 protein
基因别名: AW125761; GPRC5B; RAIG2
UniProt ID: (Mouse) Q923Z0
Entrez Gene ID: (Mouse) 64297, (Rat) 293546
positive regulation of protein phosphorylation
signal transduction
G-protein coupled receptor signaling pathway
locomotory behavior
positive regulation of neuron projection development
glucose homeostasis
positive regulation of I-kappaB kinase/NF-kappaB signaling
positive regulation of neuron differentiation
positive regulation of protein kinase activity
positive regulation of inflammatory response
positive regulation of macrophage cytokine production
positive regulation of protein tyrosine kinase activity
positive regulation of canonical Wnt signaling pathway
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