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Invitrogen
Follistatin Recombinant Rabbit Monoclonal Antibody (24GB3490)
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Follistatin Antibody (MA5-57027) in ICC/IF
Immunocytochemical staining of Follistatin in H9c2 cells using Follistatin Recombinant Monoclonal Antibody (Product # MA5-57027) at a 1:1,1000 dilution. Nuclei were stained blue with DAPI; Follistatin was stained magenta with Alexa Fluor® 647. Images were taken using Leica stellaris 5. Protein abundance based on laser intensity and smart gain: Low. Scale bar: 20 μm.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA5-57027
产品规格
种属反应
Human,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293F
分类
Recombinant Monoclonal
类型
Antibody
克隆号
24GB3490
抗原
A synthesized peptide derived from human Follistatin (aa 1-150)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1.55 mg/mL
规格
155 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Dry ice (international)
RRID
靶标信息
Follistatin is a single-chain gonadal protein that specifically inhibits follicle-stimulating hormone release. The single FST gene encodes two isoforms, FST317 and FST344 containing 317 and 344 amino acids respectively, resulting from alternative splicing of the precursor mRNA. In a study in which 37 candidate genes were tested for linkage and association with polycystic ovary syndrome (PCOS) or hyperandrogenemia in 150 families, evidence was found for linkage between PCOS and follistatin.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Activin-binding protein; Follictatin; Follistatin; follistatin-A; FS
基因别名: FOL1; FST; Fst-288; RATFOL1
UniProt ID: (Rat) P21674
Entrez Gene ID: (Rat) 24373
negative regulation of transcription from RNA polymerase II promoter
skeletal system development
hematopoietic progenitor cell differentiation
gamete generation
pattern specification process
female gonad development
BMP signaling pathway
hair follicle morphogenesis
negative regulation of activin receptor signaling pathway
odontogenesis of dentin-containing tooth
keratinocyte proliferation
negative regulation of cell differentiation
negative regulation of follicle-stimulating hormone secretion
positive regulation of hair follicle development
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