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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Coreceptor for SEMA3A, SEMA3C, SEMA3F and SEMA6D. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm. [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Plex 1; plexin 1; plexin A1; plexin-1; Plexin-A1; Semaphorin receptor NOV
基因别名: 2600013D04Rik; Kiaa4053; mKIAA4053; NOV; PlexA1; PLXN1; PLXNA1; RGD1560871
UniProt ID: (Mouse) P70206
Entrez Gene ID: (Rat) 362398, (Mouse) 18844