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Invitrogen
RNF40 Recombinant Rabbit Monoclonal Antibody (24GB1100)
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FIGURE: 1 / 3
RNF40 Antibody (MA5-57699) in ICC/IF
Immunocytochemical staining of RNF40 in HepG2 cells using RNF40 Recombinant Monoclonal Antibody (Product # MA5-57698) at a 1:1,1000 dilution. Nuclei were stained blue with DAPI; RNF40 was stained magenta with Alexa Fluor® 647. Images were taken using Leica stellaris 5. Protein abundance based on laser Intensity and smart gain: Medium. Scale bar: 20 μm.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA5-57699
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293F
Class
Recombinant Monoclonal
Type
Antibody
Clone
24GB1100
Immunogen
A synthesized peptide derived from human RNF40 (aa 220-450)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1.5 mg/mL
Amount
30 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Dry ice (international)
RRID
Target Information
The protein encoded by this gene contains a RING finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein was reported to interact with the tumor suppressor protein RB1. Studies of the rat counterpart suggested that this protein may function as an E3 ubiquitin-protein ligase, and facilitate the ubiquitination and degradation of syntaxin 1, which is an essential component of the neurotransmitter release machinery.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 95 kDa retinoblastoma-associated protein; BRE1-B; DKFZp686K191; E3 ubiquitin-protein ligase BRE1B; MGC13051; Protein staring; RBP95; RING finger protein 40; RING-type E3 ubiquitin transferase BRE1B; staring protein; Syntaxin-1-interacting RING finger protein
Gene Aliases: AI848422; BRE1B; KIAA0661; mKIAA0661; RNF40
UniProt ID: (Rat) Q8CJB9, (Mouse) Q3U319
Entrez Gene ID: (Rat) 266712, (Mouse) 233900
mRNA 3'-UTR binding
ubiquitin-protein transferase activity
protein binding
zinc ion binding
ligase activity
syntaxin-1 binding
ubiquitin protein ligase binding
protein complex binding
protein homodimerization activity
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
ribosomal S6-glutamic acid ligase activity
ubiquitin conjugating enzyme binding
coenzyme F420-0 gamma-glutamyl ligase activity
coenzyme F420-2 alpha-glutamyl ligase activity
metal ion binding
protein-glycine ligase activity
protein-glycine ligase activity, initiating
protein-glycine ligase activity, elongating
tubulin-glycine ligase activity
protein-glutamic acid ligase activity
tubulin-glutamic acid ligase activity
ubiquitin-dependent protein catabolic process
regulation of mitotic cell cycle
histone monoubiquitination
histone H2B ubiquitination
negative regulation of mRNA polyadenylation
positive regulation of histone H2B ubiquitination
chromatin modification
positive regulation of proteasomal protein catabolic process
positive regulation of protein polyubiquitination
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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