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Invitrogen
UBE2L3 Recombinant Rabbit Monoclonal Antibody (24GB1875)
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FIGURE: 1 / 4
UBE2L3 Antibody (MA5-57813) in ICC/IF
Immunocytochemical staining of UBE2L3 in HepG2 cells using UBE2L3 Recombinant Monoclonal Antibody (Product # MA5-57812) at a 1:1,1000 dilution. Nuclei were stained blue with DAPI; UBE2L3 was stained magenta with Alexa Fluor® 647. Images were taken using Leica stellaris 5. Protein abundance based on laser Intensity and smart gain: Medium. Scale bar: 20 μm.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA5-57813
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293F
Class
Recombinant Monoclonal
Type
Antibody
Clone
24GB1875
Immunogen
A synthesized peptide derived from human UBE2L3 (aa 130-154)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.2 mg/mL
Amount
4 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Dry ice (international)
RRID
Target Information
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). UBE2L3 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is demonstrated to participate in the ubiquitination of p53, c-Fos, and the NF-kB precursor p105 in vitro.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: E2 ubiquitin-conjugating enzyme L3; L-UBC; UbcH7; UbcM4; Ubiquitin carrier protein L3; ubiquitin-conjugating enzyme 7; Ubiquitin-conjugating enzyme E2 L3; Ubiquitin-conjugating enzyme E2-F1; Ubiquitin-protein ligase L3
Gene Aliases: C79827; UBCE7; UBCH7; UbcM4; UBE2L3
UniProt ID: (Mouse) P68037
Entrez Gene ID: (Rat) 363836, (Mouse) 22195
protein polyubiquitination
regulation of transcription, DNA-templated
metabolic process
cell proliferation
protein ubiquitination
positive regulation of protein ubiquitination
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
cell cycle phase transition
positive regulation of ubiquitin-protein transferase activity
protein K11-linked ubiquitination
cellular response to steroid hormone stimulus
cellular response to glucocorticoid stimulus
positive regulation of protein targeting to mitochondrion
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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