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Invitrogen
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Immunogen sequence: PWDPGLTARD LLFRGGCRYR KRPRVVLDVT EQISRFLLDH GDVAFAPLGK LMLENFKLEG AGSRTKKKTV VSVKKLLQDL GGHQPWGCPW AYLSNRQRRF SILGGPILGT SVASHLAELL HEELVLRWEQ LLLDEACTGG ALAWVPG
Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory signals. TAF1C is the largest SL1-specific TAF. Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory signals. This gene encodes the largest SL1-specific TAF. Two transcripts encoding different isoforms have been identified.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: RNA polymerase I-specific TBP-associated factor 110 kDa; TAFI110; TATA box-binding protein-associated factor 1C; TATA box-binding protein-associated factor RNA polymerase I subunit C; TATA box-binding protein-associated factor, RNA polymerase I, subunit C; TBP-associated factor 1C; Transcription initiation factor SL1/TIF-IB subunit C
基因别名: TAF1C
UniProt ID: (Rat) Q6P773
Entrez Gene ID: (Rat) 361420