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Invitrogen
CD299 (DC-SIGN/L) Recombinant Rabbit Monoclonal Antibody (4O9A4)
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CD299 (DC-SIGN/L) Antibody (MA5-58219) in ICC/IF
Immunocytochemistry analysis of CD299 (DC-SIGN/L) using 293T cells. The cells were incubated using 1:200 dilution with CD299 (DC-SIGN/L) Recombinant Monoclonal Antibody (Product # MA5-58220) (100x lens). Followed by further incubation with Cy3-conjugated Goat anti-Rabbit IgG (H+L) using a 1:500 dilution (Red). DAPI was used for nuclear staining (Blue).
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA5-58219
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
4O9A4
抗原
Recombinant protein (or fragment).
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1.61 mg/mL
规格
32.2 µg
纯化类型
Protein A
保存液
PBS, pH 7.3, with 0.05% BSA, 50% glycerol
内含物
0.09% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Dry ice (international)
RRID
产品详细信息
Immunogen sequence: QVSKVPSSLS QEQSEQDAIY QNLTQLKAAV GELSEKSKLQ EIYQELTQLK AAVGELPEKS KLQEIYQELT RLKAAVGELP EKSKLQEIYQ ELTRLKAAVG ELPEKSKLQE IYQELTRLKA AVGELPEKSK LQEIYQELTE LKAAVGELPE KSKLQEIYQE LTQLKAAVGE LPDQSKQQQI YQELTDLKTA FERLCRHCPK DWTFFQGNCY FMSNSQRNWH DSVTACQEVR AQLVVIKTAE EQNFLQLQTS RSNRFSWMGL SDLNQEGTWQ WVDGSPLSPS FQRYWNSGEP NNSGNEDCAE FSGSGWNDNR CDVDNYWICK KPAACFRDE
靶标信息
CLEC4M is a type II integral membrane protein that is 77% identical to CD209 antigen, a HIV gp120-binding protein. This protein, like CD209, efficiently binds both intercellular adhesion molecule 3 (ICAM3) and HIV-1 gp120, and enhances HIV-1 infection of T cells.Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests.This gene encodes a type II integral membrane protein that is 77% identical to CD209 antigen, a HIV gp120-binding protein. This protein, like CD209, efficiently binds both intercellular adhesion molecule 3 (ICAM3) and HIV-1 gp120, and enhances HIV-1 infection of T cells. This gene is mapped to 19p13.3, in a cluster with the CD209 and CD23/FCER2 genes. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: C-type lectin domain family 4 member M; CD209 antigen-like protein 1; CD299; DC-SIGN-related protein; DC-SIGN2; DC-SIGNR; Dendritic cell-specific ICAM-3-grabbing non-integrin 2; L-SIGN; Liver/lymph node-specific ICAM-3-grabbing non-integrin; MGC129964; MGC47866
基因别名: CD209L; CD209L1; CD299; CLEC4M
Entrez Gene ID: (Human) 10332
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