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Invitrogen
CXC-ELR (Biosimilar) Recombinant Human Monoclonal Antibody
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产品信息
MA5-58954
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Human
/ IgG4SP
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Lyophilized
浓度
1 mg/mL
规格
1 mg
纯化类型
Protein A
保存液
25mM histidine, pH 6.2, with 8% sucrose, 0.01% Tween 80
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Dry ice (international)
RRID
产品详细信息
For reconstitution, add sterile, distilled water to achieve a final antibody concentration of 1 mg/mL. Gently shake to solubilize the protein completely. Do not vortex. Reconstituted products should be stored at -80 °.
This antibody can also be cross referenced by the term Lilly patent anti-Pan-ELR+.
靶标信息
CXC-ELR chemokines are a subgroup of CXC chemokines characterized by the presence of a conserved Glu-Leu-Arg (ELR) motif immediately preceding the CXC sequence. ELR-positive CXC chemokines, such as CXCL1, CXCL2, CXCL5, and CXCL8 (IL-8), are potent promoters of angiogenesis and neutrophil recruitment. These chemokines primarily signal through CXCR1 and CXCR2 receptors on neutrophils and endothelial cells, mediating chemotaxis, inflammation, and vascular growth. Due to their pro-inflammatory and pro-angiogenic properties, CXC-ELR chemokines play important roles in host defense, wound healing, tumor progression, and chronic inflammatory diseases.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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