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Invitrogen
Endothelin B Receptor (Biosimilar) Recombinant Human Monoclonal Antibody
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产品信息
MA5-58998
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Human
/ IgG1
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Lyophilized
浓度
1 mg/mL
规格
1 mg
纯化类型
Protein A
保存液
25mM histidine, pH 6.2, with 0.01% Tween 80, 8% sucrose
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Dry ice (international)
RRID
产品详细信息
For reconstitution, add sterile, distilled water to achieve a final antibody concentration of 1 mg/mL. Gently shake to solubilize the protein completely. Do not vortex. Reconstituted products should be stored at -80 °.
This antibody can also be cross referenced by the term DEDN6526A.
靶标信息
Non-specific receptor for endothelin 1, 2, and 3. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: AU022549; Endothelin receptor non-selective type; endothelin receptor subtype B1; Endothelin receptor type B; ET-B; Et-b receptor; Et-b-r; ET-RB; Etb receptor; Etb-svr; G-protein coupled receptor; Hirschsprung disease 2; RP11-318G21.1; unnamed protein product
基因别名: ABCDS; EDNRB; ET-B; ET-BR; ETB; ETB1; ETBR; ETRB; HSCR; HSCR2; WS4A
UniProt ID: (Human) P24530
Entrez Gene ID: (Human) 1910
negative regulation of transcription from RNA polymerase II promoter
neural crest cell migration
renin secretion into blood stream
regulation of heart rate
regulation of pH
signal transduction
cell surface receptor signaling pathway
G-protein coupled receptor signaling pathway
negative regulation of adenylate cyclase activity
phospholipase C-activating G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
nervous system development
peripheral nervous system development
posterior midgut development
regulation of blood pressure
positive regulation of cell proliferation
gene expression
negative regulation of neuron maturation
vein smooth muscle contraction
vascular smooth muscle contraction
calcium-mediated signaling
cGMP-mediated signaling
heparin metabolic process
melanocyte differentiation
regulation of fever generation
aldosterone metabolic process
response to lipopolysaccharide
enteric smooth muscle cell differentiation
positive regulation of urine volume
renal sodium excretion
epithelial fluid transport
vasoconstriction
vasodilation
negative regulation of apoptotic process
positive regulation of I-kappaB kinase/NF-kappaB signaling
pigmentation
developmental pigmentation
macrophage chemotaxis
response to pain
enteric nervous system development
regulation of epithelial cell proliferation
negative regulation of protein metabolic process
sodium ion homeostasis
canonical Wnt signaling pathway
positive regulation of penile erection
establishment of endothelial barrier
renal sodium ion absorption
calcium ion transmembrane transport
cellular response to lipopolysaccharide
protein transmembrane transport
glomerular visceral epithelial cell differentiation
endothelin receptor signaling pathway
renal albumin absorption
neuroblast migration
chordate pharynx development
response to sodium phosphate
response to endothelin
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