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Invitrogen
FGF1 Monoclonal Antibody (C14)
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FIGURE: 1 / 2
FGF1 Antibody (MA566054) in IHC (P)
Immunohistochemistry analysis of FGF1 in paraffin-embedded Human Cardiac Muscle tissue. Samples were incubated with FGF1 Monoclonal (Product # MA566054) antibody using a dilution of 20 µg/mL, followed by HRP-Linked Caprine Anti-Mouse IgG (2 µg/mL) and DAB.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA566054
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Pig
Host/Isotype
Mouse
/ IgG1, kappa
Class
Monoclonal
Type
Antibody
Clone
C14
Immunogen
Recombinant Fibroblast Growth Factor 1, Acidic (FGF1) (Met1-Asp155)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
200 µg
Purification
Protein A/G
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
FGF1 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is thought to be involved in organogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Acidic fibroblast growth factor; aFGF; ECGF; Endothelial cell growth factor; FGF; FGF-1; Fibroblast growth factor; Fibroblast growth factor 1; H-FGF-a; HBGF-1; Heparin-binding growth factor 1; M-FGF-a
Gene Aliases: AFGF; FGF-1; FGF1; FGFA
Entrez Gene ID: (Pig) 397497
activation of MAPK activity
angiogenesis
positive regulation of cell proliferation
fibroblast growth factor receptor signaling pathway
positive regulation of endothelial cell migration
cell differentiation
positive regulation of cell migration
activation of protein kinase B activity
cellular response to heat
positive regulation of cholesterol biosynthetic process
positive regulation of angiogenesis
positive regulation of transcription from RNA polymerase II promoter
positive regulation of cell division
branch elongation involved in ureteric bud branching
mesonephric epithelium development
regulation of endothelial tube morphogenesis
positive regulation of intracellular signal transduction
positive regulation of sprouting angiogenesis
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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