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Invitrogen
Nosiheptide Recombinant Mouse Monoclonal Antibody (4F6)
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FIGURE: 1 / 1
Nosiheptide Antibody (MA566395) in SDS-PAGE
SDS-PAGE characterization of Nosiheptide under reducing conditions. Lane M: Protein marker (kDa); Lane NSP: Purified Nosiheptide Recombinant Monoclonal (Product # MA566395). Nosiheptide showing heavy chain (~50 kDa) and light chain (~25 kDa). Gels were stained with Coomassie Brilliant Blue R-445.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA566395
Product Specifications
Species Reactivity
Chemical
Host/Isotype
Mouse
/ IgG
Expression System
CHO cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
4F6
Immunogen
Conjugate of NSP hapten and KLH.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
9.2 mg/mL
Amount
200 µg
Purification
Protein G
Storage buffer
PBS
Contains
0.09% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
Nosiheptide is a potent thiopeptide antibiotic characterized by a macrocyclic core containing a 6-membered heterocycle central to multiple azoles and dehydroamino acids. It is produced through ribosomal synthesis followed by post-translational modifications (PTMs) of precursor peptides, which contribute to its structural complexity. The biosynthesis of nosiheptide involves a class C radical S-adenosylmethionine methylase, NosN, which catalyzes carbon transfer to C4 of 3-methylindolic acid, completing the side-ring system. Nosiheptide exhibits excellent bactericidal activity against Gram-positive bacteria, although its physical and chemical properties limit its clinical application. Research continues to explore its biosynthetic pathway and potential analogues for antibacterial use.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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