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Invitrogen
Indometacin Recombinant Mouse Monoclonal Antibody (2B11)
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Indometacin Antibody (MA566453) in SDS-PAGE
SDS-PAGE characterization of Indometacin under reducing conditions. Lane M: Protein marker (kDa); Lane IDM: Purified Indometacin Recombinant Monoclonal (Product # MA566453). Indometacin showing heavy chain (~50 kDa) and light chain (~25 kDa). Gels were stained with Coomassie Brilliant Blue R-635.
产品信息
MA566453
产品规格
种属反应
Chemical
宿主/亚型
Mouse
/ IgG
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
2B11
抗原
Conjugate of IDM hapten and KLH.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
8.3 mg/mL
规格
200 µg
纯化类型
Protein G
保存液
PBS
内含物
0.09% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
Indometacin, also known as indomethacin, is a non-steroidal anti-inflammatory drug (NSAID) primarily used to reduce fever, pain, stiffness, and swelling. It functions by inhibiting the cyclooxygenase (COX) enzymes, which are involved in the synthesis of prostaglandins, thereby reducing inflammation and pain. Indometacin is often formulated with various delivery systems, such as biomimetic silica xerogel and self-assembled prodrug nanoparticles, to enhance its release and reduce toxicity. These formulations aim to improve its bioavailability and therapeutic efficacy while minimizing gastrointestinal side effects. Indometacin's gene-related information is not directly applicable as it is a small molecule drug rather than a biologic or biosimilar. However, its analogs are being synthesized to selectively inhibit COX-2, offering potential for reduced ulcer liability and improved safety profiles.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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