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Invitrogen
Hexachlorobenzene Recombinant Mouse Monoclonal Antibody (6F11)
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Hexachlorobenzene Antibody (MA566465) in SDS-PAGE
SDS-PAGE characterization of Hexachlorobenzene under reducing conditions. Lane M: Protein marker (kDa); Lane HCB: Purified Hexachlorobenzene Recombinant Monoclonal (Product # MA566465). Hexachlorobenzene showing heavy chain (~50 kDa) and light chain (~25 kDa). Gels were stained with Coomassie Brilliant Blue R-385.
产品信息
MA566465
产品规格
种属反应
Chemical
宿主/亚型
Mouse
/ IgG
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
6F11
抗原
Conjugate of HCB hapten and KLH.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
7.4 mg/mL
规格
200 µg
纯化类型
Protein G
保存液
PBS
内含物
0.09% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
Hexachlorobenzene (HCB) is an organochlorine compound known for its persistence in the environment and its bioaccumulation in living organisms. It was initially used as a fungicide but has been banned due to its slow biodegradation and potential health risks. Structurally, HCB is a chlorinated aromatic compound with six chlorine atoms attached to a benzene ring, making it highly stable and resistant to breakdown. Functionally, HCB acts through the aryl hydrocarbon receptor (AhR), leading to translocation to the nucleus and modulation of gene expression, similar to dioxin-like compounds. This interaction can trigger various cellular responses, including activation of c-Src kinase activity. Despite its ban, HCB residues are still found in the environment, posing risks to human health and wildlife.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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