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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Fenthion is an organophosphate insecticide that undergoes metabolic transformation primarily through the action of flavin-containing monooxygenase 1 (FMO1), which catalyzes its oxidation to fenthion sulfoxide in a stereoselective manner. The gene expression related to DNA repair pathways, such as Rad18 and Xrcc2, is affected by fenthion exposure, indicating its potential genotoxic effects. Fenthion and its metabolites, including fenthion oxon, fenthion oxon sulfoxide, and fenthion sulfone, can be analyzed using ultra-high performance liquid chromatography-tandem mass spectrometry. The molecular structure of fenthion and its derivatives is crucial for understanding their biochemical interactions and environmental impact. The degradation pathways of fenthion involve complex interactions with various precursor species, highlighting the importance of studying its environmental fate and toxicity.
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