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Invitrogen
Carbamazepine Recombinant Mouse Monoclonal Antibody (4E5)
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FIGURE: 1 / 1
Carbamazepine Antibody (MA566597) in SDS-PAGE
SDS-PAGE characterization of Carbamazepine under reducing conditions. Lane M: Protein marker (kDa); Lane CMZ: Purified Carbamazepine Recombinant Monoclonal (Product # MA566597). Carbamazepine showing heavy chain (~50 kDa) and light chain (~25 kDa). Gels were stained with Coomassie Brilliant Blue R-620.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA566597
Product Specifications
Species Reactivity
Chemical
Host/Isotype
Mouse
/ IgG
Expression System
CHO cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
4E5
Immunogen
Conjugate of CMZ hapten and KLH.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
5.2 mg/mL
Amount
200 µg
Purification
Protein G
Storage buffer
PBS
Contains
0.09% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
Carbamazepine is an anticonvulsant medication primarily used in the treatment of epilepsy and neuropathic pain. It functions by stabilizing inactive sodium channels in the brain, thereby reducing neuronal excitability. The drug is metabolized in the liver, and its active metabolite, carbamazepine-10,11-epoxide, contributes to its therapeutic effects. Carbamazepine is known for its enzyme-inducing properties, which can affect the metabolism of other drugs. Biosimilar formulations of carbamazepine, such as Taver® by MEDOCHEMIE, have been compared to the innovator product, Tegretol® by NOVARTIS, in terms of concentration over dose ratio, indicating potential differences in efficacy and safety profiles. Despite being considered bioequivalent in single-dose studies, these formulations may not maintain equivalence in a steady-state patient population. The development of photoswitchable carbamazepine analogs aims to reduce systemic side effects by allowing non-invasive neuroinhibition. This highlights the ongoing efforts to improve the safety and efficacy of carbamazepine and its biosimilars.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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