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Invitrogen
Amantadine Recombinant Mouse Monoclonal Antibody (6G1)
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FIGURE: 1 / 1
Amantadine Antibody (MA566642) in SDS-PAGE
SDS-PAGE characterization of Amantadine under reducing conditions. Lane M: Protein marker (kDa); Lane AMS: Purified Amantadine Recombinant Monoclonal (Product # MA566642). Amantadine showing heavy chain (~50 kDa) and light chain (~25 kDa). Gels were stained with Coomassie Brilliant Blue R-386.
Product Details
MA566642
Product Specifications
Species Reactivity
Chemical
Host/Isotype
Mouse
/ IgG
Expression System
CHO cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
6G1
Immunogen
Conjugate of AMS hapten and KLH.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
7.1 mg/mL
Amount
200 µg
Purification
Protein G
Storage buffer
PBS
Contains
0.09% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
Amantadine is a well-established antiviral and antiparkinsonian agent, primarily targeting the NMDA receptor to exert its therapeutic effects. It is located on chromosome 1 at the locus 1p36.23, and its chemical structure is characterized by a tricyclic amine with a cage-like adamantane core, which contributes to its unique pharmacokinetic properties. Functionally, amantadine blocks viral replication by interfering with the viral M2 protein, and in Parkinson's disease, it modulates dopaminergic transmission, providing symptomatic relief. Recent studies have explored its hybridization with gardenamide A to enhance NMDA antagonism, indicating potential for expanded therapeutic applications. The development of biosimilar versions aims to improve accessibility and reduce costs associated with amantadine therapy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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