Search
Invitrogen
KIR2DL2/KIR2DL3 Recombinant Rabbit Monoclonal Antibody (6W7Q7)
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
图: 1 / 7
KIR2DL2/KIR2DL3 Antibody (MA569290) in ICC/IF
Immunocytochemical analysis of KIR2DL2/KIR2DL3 in 293F-KIR2DL3 and 293F cells. Samples were incubated with KIR2DL2/KIR2DL3 recombinant monoclonal antibody (Product # MA569290) using a dilution of 1:200 (40x lens). DAPI was used for nuclear staining (Blue).
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA569290
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
6W7Q7
抗原
Recombinant protein (or fragment).
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1.09 mg/mL
规格
109 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3., with 50% glycerol
内含物
0.09% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
KIR2DL2 and KIR2DL3 are genes belonging to the killer cell immunoglobulin-like receptor (KIR) family, located on chromosome 19q13.4. They encode inhibitory receptors expressed primarily on natural killer (NK) cells and a subset of T cells. The proteins produced by these genes play a key role in regulating the immune response through their interaction with human leukocyte antigen (HLA) class I molecules, specifically HLA-C alleles. KIR2DL2 recognizes a broad range of HLA-C alleles with a lysine at position 80 (C1 group), while KIR2DL3 has a higher affinity for the HLA-C1 group. Structurally, these receptors consist of two extracellular immunoglobulin-like domains, a transmembrane region, and a long cytoplasmic tail that contains immunoreceptor tyrosine-based inhibitory motifs (ITIMs). Upon ligand binding, these receptors transmit inhibitory signals to prevent NK cell activation, thereby protecting healthy cells from immune destruction.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
