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Invitrogen
MYH6/MYH7 Recombinant Rabbit Monoclonal Antibody (10J6U7)
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图: 1 / 6
MYH6/MYH7 Antibody (MA569547) in IHC (P)
Immunohistochemistry analysis of MYH6/MYH7 on paraffin-embedded Mouse heart tissue. Samples were incubated with MYH6/MYH7 recombinant monoclonal antibody (Product # MA569546) using a dilution of 1:800 (40x lens). Followed by a further incubation with Cy3 Goat Anti-Rabbit IgG (H+L) using a dilution of 1:500 (Red). DAPI was used for nuclear staining (Blue). High pressure antigen retrieval performed with 0. 01... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA569547
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
10J6U7
抗原
Synthetic peptide.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1.32 mg/mL
规格
26.4 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3., with 50% glycerol, 0.05% BSA
内含物
0.09% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
Cardiac muscle myosin is a hexamer consisting of two heavy chain subunits, two light chain subunits, and two regulatory subunits. This gene encodes the alpha heavy chain subunit of cardiac myosin. The gene is located 4kb downstream of the gene encoding the beta heavy chain subunit of cardiac myosin. Mutations in this gene cause familial hypertrophic cardiomyopathy and atrial septal defect 3.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: alpha cardiac MHC; alpha myosin; beta myosin heavy chain; cardiac myosin heavy chain alpha isoform; cardiac myosin heavy chain beta isoform; cardiomyopathy, hypertrophic 1; MYH-beta/slow; MyHC-alpha; MyHC-beta; MyHC-slow; Myosin heavy chain 6; Myosin heavy chain 7; myosin heavy chain polypeptide 6 cardiac muscle adult; myosin heavy chain polypeptide 7 cardiac muscle fetal; Myosin heavy chain slow isoform; Myosin heavy chain, cardiac muscle alpha isoform; Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha); Myosin heavy chain, cardiac muscle beta isoform; myosin heavy chain, cardiac muscle, adult; myosin heavy chain, cardiac muscle, fetal; myosin heavy chain, polypeptide 6, cardiac muscle, alpha; myosin heavy chain, polypeptide 7; myosin, heavy polypeptide 6, cardiac muscle, alpha; myosin, heavy polypeptide 7, cardiac muscle, beta; Myosin-6; Myosin-7
基因别名: A830009F23Rik; AA517445; alpha-MHC; B-MHC; beta-MHC; MYH6; MYH7; Myhc-a; Myhc-b; MyHC-I; MYHCA; MYHCB
UniProt ID: (Mouse) Q02566, (Mouse) Q91Z83, (Rat) P02564
Entrez Gene ID: (Mouse) 17888, (Rat) 29556, (Mouse) 140781, (Rat) 29557
microfilament motor activity
nucleotide binding
motor activity
actin binding
protein binding
calmodulin binding
ATP binding
ATPase activity
protein kinase binding
actin-dependent ATPase activity
calcium-dependent ATPase activity
identical protein binding
protein homodimerization activity
protein heterodimerization activity
non-receptor serine/threonine protein kinase
in utero embryonic development
regulation of the force of heart contraction
regulation of heart rate
muscle contraction
striated muscle contraction
adult heart development
visceral muscle development
regulation of heart contraction
metabolic process
regulation of blood pressure
actin filament-based movement
muscle filament sliding
myofibril assembly
BMP signaling pathway
regulation of ATPase activity
sarcomere organization
ATP metabolic process
cardiac muscle fiber development
atrial cardiac muscle tissue morphogenesis
ventricular cardiac muscle tissue morphogenesis
cardiac muscle contraction
canonical Wnt signaling pathway
regulation of heart growth
response to heat
skeletal muscle contraction
regulation of the force of skeletal muscle contraction
transition between fast and slow fiber
regulation of slow-twitch skeletal muscle fiber contraction
response to reactive oxygen species
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
