Hamburger Menu Button
Thermo Fisher Scientific Logo
登录
没有账号?建立账号 注册
  • 产品
    • 抗体
    • 引物合成
    • GeneArt Gene Synthesis Instant Designer
    • TaqMan Assay and Array Search
    • PCR 设备和耗材
    • 色谱柱和纯化柱
    • 实验室离心机
    • 分子生物学试剂和试剂盒
    • 实验室塑料耗材及用品
    • 查看所有产品分类
  • 应用和技术
    • 色谱
    • 细胞转染和培养
    • 实时荧光定量PCR
    • 质谱
    • 实验室塑料耗材及用品
    • 电子显微镜
    • 蛋白质生物学
    • PCR
    • RNAi
    • 环境
    • 查看所有应用和技术
  • 服务
    • 定制服务
    • 企业级实验室信息化服务
    • 金融&租赁服务
    • 仪器服务
    • OEM和商业供应
    • 培训服务
    • 360° CDMO 和 CRO 服务
    • CDMO 服务
    • 临床试验 CRO 服务
    • Unity Lab Services
    • 查看所有帮助和支持
  • 帮助和支持
    • 学习中心
    • 联系我们
    • 更改国家或地区
    • 查看所有帮助和支持
  • 热门产品
    • TaqMan Real-Time PCR Assays
      TaqMan 实时荧光定量 PCR 试剂盒
    • Antibodies
      抗体
    • Oligos, Primers & Probes
      寡核苷酸、引物、探针
    • GeneArt Gene Synthesis
      GeneArt 基因合成
    • Cell Culture Plastics
      细胞培养耗材
  • Who We Serve
    • 抗体治疗解决方案
    • 细胞与基因治疗解决方案
    • 学术科研
    • 工业与应用
  • 联系我们
  • 货号直购
  • 订单查询
  • 查找文件&证书
Thermo Fisher Scientific Logo

Search

搜索全部或下列指定分类
Search button
          • 联系我们
          • 货号直购
          • 登录
            登录
            没有账号?建立账号 注册
            • 我的账号
            • 订单
            • 会员中心
            • 账单及发票查询
            • 定制产品及项目
          • Primary Antibodies ›
          • PKC Pan Antibodies

          Invitrogen

          Phospho-PKC Pan (Ser660) Recombinant Rabbit Monoclonal Antibody (4G2I2)

          查看其他8个PKC Pan抗体

          {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}

          {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}

          {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}

          说明书
          Certificates
          实验方案
          问题与答案
          技术支持
          说明书
          Certificates
          实验方案
          问题与答案
          技术支持
          说明书
          Certificates
          实验方案
          问题与答案
          技术支持

          Cite Phospho-PKC Pan (Ser660) Recombinant Rabbit Monoclonal Antibody (4G2I2)

          Additional Information:
          {{banner.description}}
          {{$ctrl.isSkuNotesCollapsed ? 'View more' : 'View less'}}
          • 抗体检测数据 (5)
          Phospho-PKC Pan (Ser660) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.
          Phospho-PKC Pan (Ser660) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          图: 1 / 5

          {{ $ctrl.currentElement.advancedVerification.fullName }}
          {{ $ctrl.currentElement.advancedVerification.text }}

          Phospho-PKC Pan (Ser660) Antibody (MA569877) in IHC (P)

          Immunohistochemistry analysis of Phospho-PKC Pan (Ser660) on paraffin-embedded Mouse spleen tissue. Samples were incubated with Phospho-PKC Pan (Ser660) recombinant monoclonal antibody (Product # MA569876) using a dilution of 1:400 (40x lens). High pressure antigen retrieval performed with 0. 01 M Tris-EDTA Buffer (pH 9. 0). {{ $ctrl.currentElement.advancedVerification.fullName }} 验证信息 View more
          已发表图片由___提供 benchsci-logo
          PMID: {{$ctrl.currentElement.benchSciPubmedId}}
          查看产品

          {{$ctrl.videoDesc}}

          {{$ctrl.videoLongDesc}}

          Phospho-PKC Pan (Ser660) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Phospho-PKC Pan (Ser660) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Phospho-PKC Pan (Ser660) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Phospho-PKC Pan (Ser660) Antibody in Western Blot (WB)
          Phospho-PKC Pan (Ser660) Antibody in Western Blot (WB)

          Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.

          产品信息

          MA569877

          应用
          建议稀释比
          已发表文章

          免疫印迹 (WB)

          1:500-1:1,000
          -

          免疫组化(石蜡) (IHC (P))

          1:100-1:500
          -

          酶联免疫吸附实验 (ELISA)

          1 µg/mL
          -
          产品规格

          种属反应

          Human, Mouse, Rat

          宿主/亚型

          Rabbit / IgG

          Expression System

          HEK293 cells

          分类

          Recombinant Monoclonal

          类型

          Antibody

          克隆号

          4G2I2

          抗原

          Synthetic peptide.

          偶联物

          Unconjugated Unconjugated Unconjugated

          形式

          Liquid

          浓度

          1.34 mg/mL

          规格

          26.8 µg

          纯化类型

          Affinity chromatography

          保存液

          PBS, pH 7.3., with 50% glycerol

          内含物

          0.05% ProClin 300

          保存条件

          -20°C, Avoid Freeze/Thaw Cycles

          运输条件

          Ambient (domestic); Wet ice (international)

          靶标信息

          Members of the protein kinase C (PKC) family play a key regulatory role in a variety of cellular functions including cell growth and differentiation, gene expression, hormone secretion and membrane function. PKCs were originally identified as serine/threonine protein kinases whose activity was dependent on calcium and phospholipids. Diacylglycerols (DAG) and tumor promoting phorbol esters bind to and activate PKC. PKCs can be subdivided into at least two major classes including conventional (c) PKC isoforms ( alpha, betaI, betaII and gamma) and novel (n) PKC isoforms ( delta, epsilon, zeta, eta and theta). Patterns of expression for each PKC isoform differ among tissues and PKC family members exhibit clear differences in their cofactor dependencies. For instance, the kinase activities of nPKC delta and epsilon are independent of Ca2+.

          仅用于科研。不用于诊断过程。未经明确授权不得转售。

          篇参考文献 (0)

          您是否在文献中引用过该产品?请点击下方按钮邮件告知我们。
          引用该产品

          生物信息学

          蛋白别名: 14 - 3 - 3 - zeta isoform; aPKC-lambda/iota; atypical protein kinase C; Atypical protein kinase C-lambda/iota; nPKC-delta; nPKC-epsilon; nPKC-eta; nPKC-iota; nPKC-theta; nPKC-zeta; PKC theta; PKC zeta; PKC-A; PKC-alpha; PKC-B; PKC-beta; PKC-gamma; PKC-L; PRKC-lambda/iota; Protein kinase C alpha type; protein kinase C beta I; protein kinase C beta II; Protein kinase C beta type; protein kinase C beta-II; Protein kinase C delta type; protein kinase C delta variant IX; Protein kinase C epsilon type; Protein kinase C eta type; Protein kinase C gamma type; Protein kinase C iota type; Protein kinase C theta type; protein kinase C type I (gamma type); protein kinase C zeta subspecies; Protein kinase C zeta type; protein kinase C, beta 1; protein kinase C, delta IV; protein kinase C, delta V; protein kinase C, lambda; protein kinase c-alpha; protein kinase C-eta; protein kinase C[d]; Tyrosine-protein kinase PRKCD

          查看更多 收起

          基因别名: 14-3-3-zetaisoform; 2310021H13Rik; 5830406C15Rik; A130035A12Rik; A130082F03Rik; AI098070; AI385711; AI427505; AI875142; aPKClambda; aPKCzeta; AW494342; C80388; D14Ertd420e; DXS1179E; mKIAA4165; nPKC-zeta; PKC; PKC-0; PKC-Beta; PKC-theta; PKC2; PKC[d]; PKC[e]; PKCA; PKCB; Pkcc; PKCD; PKCdelta; PKCE; Pkcea; PKCepsilon; PKCG; PKCgamma; Pkch; PKCI; PKCL; PKClambda; Pkcq; PKCtheta; Pkcz; PRKACA; Prkc; PRKCA; PRKCB; PRKCB1; Prkcb2; Prkcc; PRKCD; PRKCE; PRKCG; PRKCH; PRKCI; PRKCL; PRKCQ; PRKCT; PRKCZ; r14-3-3; R74924; R75156; RATPKCI; zetaPKC

          查看更多 收起

          UniProt ID: (Mouse) P20444, (Rat) P05696, (Mouse) F2Z441, (Rat) P68403, (Mouse) P28867, (Rat) P09215, (Mouse) P16054, (Rat) P09216, (Mouse) P63318, (Rat) P63319, (Mouse) P23298, (Rat) Q64617, (Mouse) Q62074, (Rat) F1M7Y5, (Mouse) Q02111, (Rat) P09217, (Mouse) Q02956

          查看更多 收起

          Entrez Gene ID: (Mouse) 18750, (Rat) 24680, (Mouse) 18751, (Rat) 25023, (Mouse) 18753, (Rat) 170538, (Mouse) 18754, (Rat) 29340, (Mouse) 18752, (Rat) 24681, (Mouse) 18755, (Rat) 81749, (Mouse) 18759, (Rat) 84006, (Rat) 85420, (Mouse) 18761, (Rat) 25522, (Mouse) 18762

          查看更多 收起

          功能
          nucleotide binding protein kinase activity protein serine/threonine kinase activity protein kinase C activity calcium-dependent protein kinase C activity protein binding ATP binding zinc ion binding kinase activity transferase activity transferase activity, transferring phosphorus-containing groups enzyme binding histone kinase activity (H3-T6 specific) metal ion binding chromatin binding protein kinase C binding calcium channel regulator activity ligand-dependent nuclear receptor transcription coactivator activity histone binding androgen receptor binding calcium-independent protein kinase C activity non-membrane spanning protein tyrosine kinase activity enzyme activator activity protein kinase binding insulin receptor substrate binding TIR domain binding actin monomer binding receptor binding SH3 domain binding receptor activator activity ethanol binding 14-3-3 protein binding protein serine/threonine/tyrosine kinase activity Ral GTPase binding phospholipid binding protein domain specific binding molecular_function potassium channel regulator activity phospholipase binding non-receptor serine/threonine protein kinase protein modifying enzyme
          参与通路
          inactivation of MAPK activity response to reactive oxygen species angiogenesis negative regulation of protein phosphorylation positive regulation of protein phosphorylation positive regulation of endothelial cell proliferation regulation of the force of heart contraction chondrocyte differentiation desmosome assembly protein phosphorylation negative regulation of protein kinase activity cellular calcium ion homeostasis apoptotic process regulation of muscle contraction cell adhesion learning or memory negative regulation of cell proliferation positive regulation of endothelial cell migration positive regulation of cardiac muscle hypertrophy phosphorylation negative regulation of translation peptidyl-serine phosphorylation peptidyl-threonine phosphorylation central nervous system neuron axonogenesis positive regulation of cell migration neutrophil chemotaxis positive regulation of lipopolysaccharide-mediated signaling pathway response to estradiol negative regulation of glial cell apoptotic process histone H3-T6 phosphorylation intracellular signal transduction peptidyl-serine autophosphorylation positive regulation of blood vessel endothelial cell migration response to ethanol positive regulation of macrophage differentiation positive regulation of angiogenesis positive regulation of cell adhesion negative regulation of heart contraction positive regulation of exocytosis positive regulation of mitotic cell cycle negative regulation of glucose import negative regulation of insulin receptor signaling pathway protein autophosphorylation regulation of receptor-mediated endocytosis positive regulation of smooth muscle cell proliferation positive regulation of inflammatory response regulation of peptidyl-tyrosine phosphorylation induction of positive chemotaxis positive regulation of synapse assembly positive regulation of ERK1 and ERK2 cascade response to interleukin-1 cellular response to carbohydrate stimulus regulation of platelet aggregation intrinsic apoptotic signaling pathway positive regulation of dense core granule biogenesis aging response to mechanical stimulus response to toxic substance response to organic cyclic compound response to peptide hormone establishment of protein localization response to antibiotic response to corticosterone response to hypoxia immune system process transcription, DNA-templated regulation of transcription, DNA-templated regulation of transcription from RNA polymerase II promoter calcium ion transport negative regulation of glucose transport regulation of dopamine secretion chromatin modification positive regulation of vascular endothelial growth factor receptor signaling pathway regulation of growth B cell activation response to drug positive regulation of I-kappaB kinase/NF-kappaB signaling B cell receptor signaling pathway positive regulation of B cell receptor signaling pathway positive regulation of NF-kappaB transcription factor activity response to glucose dibenzo-p-dioxin metabolic process response to vitamin D positive regulation of odontogenesis of dentin-containing tooth response to oxidative stress cell cycle aspartate transport immunoglobulin mediated immune response termination of signal transduction negative regulation of actin filament polymerization interleukin-10 production interleukin-12 production positive regulation of superoxide anion generation regulation of actin cytoskeleton organization collagen metabolic process cellular response to oxidative stress positive regulation of protein dephosphorylation B cell proliferation neutrophil activation regulation of phosphorylation defense response to bacterium positive regulation of apoptotic process positive regulation of MAP kinase activity negative regulation of MAP kinase activity positive regulation of MAPK cascade positive regulation of glucose import negative regulation of peptidyl-tyrosine phosphorylation negative regulation of filopodium assembly negative regulation of platelet aggregation cellular senescence positive regulation of phospholipid scramblase activity positive regulation of ceramide biosynthetic process positive regulation of glucosylceramide catabolic process positive regulation of sphingomyelin catabolic process positive regulation of response to DNA damage stimulus positive regulation of apoptotic signaling pathway response to heat response to organonitrogen compound cellular response to insulin stimulus cellular response to glucose starvation response to hydrogen peroxide positive regulation of catalytic activity response to amino acid macrophage activation involved in immune response chemosensory behavior positive regulation of epithelial cell migration positive regulation of fibroblast migration positive regulation of cell-substrate adhesion negative regulation of mitochondrial membrane potential regulation of lipid metabolic process positive regulation of actin filament polymerization lipopolysaccharide-mediated signaling pathway positive regulation of insulin secretion positive regulation of synaptic transmission, GABAergic positive regulation of cytokinesis locomotory exploration behavior TRAM-dependent toll-like receptor 4 signaling pathway cellular response to platelet-derived growth factor stimulus negative regulation of apoptotic process response to morphine positive regulation of lipid catabolic process release of sequestered calcium ion into cytosol regulation of release of sequestered calcium ion into cytosol negative regulation of release of sequestered calcium ion into cytosol cell division negative regulation of mitochondrial calcium ion concentration regulation of insulin secretion involved in cellular response to glucose stimulus positive regulation of mucus secretion cellular response to ethanol cellular response to prostaglandin E stimulus cellular response to hypoxia positive regulation of wound healing positive regulation of receptor activity positive regulation of cellular glucuronidation chemical synaptic transmission negative regulation of protein ubiquitination regulation of response to food positive regulation of mismatch repair negative regulation of protein catabolic process regulation of circadian rhythm negative regulation of neuron apoptotic process response to pain rhythmic process regulation of phagocytosis innervation negative regulation of proteasomal protein catabolic process positive regulation of macrophage derived foam cell differentiation cell differentiation positive regulation of keratinocyte differentiation positive regulation of glial cell proliferation protein kinase C signaling regulation of bicellular tight junction assembly actin filament organization multicellular organism development positive regulation of neuron projection development cell migration cellular protein localization establishment of apical/basal cell polarity eye photoreceptor cell development cell-cell junction organization Golgi vesicle budding positive regulation of establishment of protein localization to plasma membrane positive regulation of endothelial cell apoptotic process membrane protein ectodomain proteolysis inflammatory response regulation of G2/M transition of mitotic cell cycle regulation of vasoconstriction neuron differentiation positive regulation of interleukin-17 production positive regulation of interleukin-4 production response to insulin positive regulation of T cell proliferation tissue regeneration positive regulation of NF-kappaB import into nucleus positive regulation of interleukin-2 biosynthetic process respiratory burst positive regulation of protein secretion positive regulation of T cell activation positive regulation of filopodium assembly positive regulation of stress fiber assembly negative regulation of T cell apoptotic process positive regulation of T-helper 17 type immune response positive regulation of T-helper 2 cell activation microtubule cytoskeleton organization positive regulation of cell-matrix adhesion signal transduction cell surface receptor signaling pathway long-term memory positive regulation of cell proliferation insulin receptor signaling pathway establishment of cell polarity negative regulation of protein complex assembly actin cytoskeleton reorganization activation of phospholipase D activity activation of protein kinase B activity positive regulation of T-helper 2 cell differentiation positive regulation of insulin receptor signaling pathway vesicle transport along microtubule positive regulation of synaptic transmission positive regulation of protein transport protein heterooligomerization negative regulation of hydrolase activity membrane depolarization membrane hyperpolarization long-term synaptic potentiation protein localization to plasma membrane neuron projection extension positive regulation of excitatory postsynaptic potential positive regulation of T-helper 2 cell cytokine production positive regulation of interleukin-5 secretion positive regulation of interleukin-13 secretion positive regulation of interleukin-10 secretion
          It has to be done as per old AB suggested Products section.

          Disclaimer

          Close

          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          guarantee_icon

          性能保障

          只要您发现Invitrogen抗体在实验中的表现与网站或说明书的所述内容不符,您即可享受免费退换货服务。*

          了解更多
          help_icon

          随时为您服务

          获取常见问题的专家解答,或者直接联系我们的技术专家,咨询应用、设备、常规产品使用问题。

          联系技术支持
          订购 Plus Icon Minus Icon
          • 订单状态查询
          • 订单支持
          • 货号直购
          • 现货供应中心
          • 电子采购
          支持 Plus Icon Minus Icon
          • 帮助&支持
          • 联系我们 - 400 820 8982
          • 技术支持中心
          • 查找文件&证书
          • 报告网站问题
          资源 Plus Icon Minus Icon
          • 学习中心
          • 促销
          • 活动&研讨会
          • 社交媒体
          关于赛默飞 Plus Icon Minus Icon
          • 关于我们
          • 招聘 招聘
          • 投资者关系 投资者关系
          • 新闻 新闻
          • 社会责任 社会责任
          • 商标
          • 政策和通知
          品牌 Plus Icon Minus Icon
          • Thermo Scientific
          • Applied Biosystems
          • Invitrogen
          • Gibco
          • Ion Torrent
          • Unity Lab Services
          • Patheon
          • PPD
          • 服务条款
          • 隐私政策
          • 定价和运输保险政策
          © 2006-2026 Thermo Fisher Scientific Inc. All rights reserved. All trademarks are the property of Thermo Fisher Scientific and its subsidiaries unless otherwise specified.
          China flag icon
          China
          本网站销售的所有产品均不得用于人类或动物之临床诊断或治疗,仅可用于工业或者科研等非医疗目的。
             电子营业执照 | 经营证照公示 | ICP备案号:沪ICP备11003924号 | 沪公网安备 31011502006935号

          Your items have has been added!


          Host server : magellan-search-green-dd86746ff-8rs9g:80/100.66.75.30:80.
          git-commit: 04e44c58f20fafe66519586ffe6db5d8a90e52ce
          git-url: https://github.com/thermofisher/magellan-search
          git-branch: release/2.53.1-Offline