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Invitrogen
MYT1 Recombinant Rabbit Monoclonal Antibody (PSH12-97)
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FIGURE: 1 / 9
MYT1 Antibody (MA570000) in ICC/IF
Immunocytochemistry analysis of MYT1 in Neuro-2a cells. Samples were incubated with MYT1 monoclonal antibody (Product # MA570000) using a dilution of 1:50 in 1% BSA in PBST overnight at 4°C followed by Goat Anti-Rabbit IgG H&L (iFluor™ 488) at a dilution of 1:1,000. Cells were fixed in 4% paraformaldehyde for 15 minutes at room temperature, permeabilized with 0.1% Triton X-100 in PBS for 15 minutes at room temperature, then blocked with 1% BSA in 10% negative goat serum for 1 hour at room temperature. PBS instead of the primary antibody wa... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA570000
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
PSH12-97
Immunogen
Recombinant protein within human Myt1 aa 651-800.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS, pH 7.4, with 0.1% BSA, 40% glycerol
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Positive control: SH-SY5Y cell lysate, Neuro-2a cell lysate, SH-SY5Y, Neuro-2a, mouse brain tissue, mouse embryonic brain tissue, mouse embryonic eye tissue, rat brain tissue, rat embryonic brain tissue, rat embryos tissue.
Subcellular location: Nucleus.
Recommended dilution for IF-tissue samples: 1:50-1:200
Target Information
The protein encoded by this gene is a member of a family of neural specific, zinc finger-containing DNA-binding proteins. This kinase preferentially phosphorylates and inactivates cell division cycle 2 protein (CDC2), and thus negatively regulates cell cycle G2/M transition. This kinase is associated with the membrane throughout the cell cycle. Its activity is highly regulated during the cell cycle. Protein kinases AKT1/PKB and PLK (Polo-like kinase) have been shown to phosphorylate and regulate the activity of this kinase. Alternatively spliced transcript variants encoding distinct isoforms have been reported. The protein binds to the promoter regions of proteolipid proteins of the central nervous system and plays a role in the developing nervous system.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Myelin transcription factor 1; Myelin transcription factor I; MyT1; MyTI; Neural zinc finger factor 2; neural zinc finger transcription factor 2; NZF-2; PLPB1; Proteolipid protein-binding protein
Gene Aliases: KIAA0835; KIAA1050; MTF1; MYT1; MYTI; Nzf2; Nzf2a; Nzf2b; Nztf2; PLPB1
UniProt ID: (Mouse) Q8CFC2
Entrez Gene ID: (Mouse) 17932, (Rat) 362291
RNA polymerase II regulatory region sequence-specific DNA binding
enhancer sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
zinc ion binding
metal ion binding
zinc finger transcription factor
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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