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Invitrogen
CaMKII delta Recombinant Rabbit Monoclonal Antibody (25GB605)
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FIGURE: 1 / 3
CaMKII delta Antibody (MA570446) in WB
Western blot analysis of CaMKII delta. Samples (HT-1080, HepG2, HeLa, H9C2, NIH/3T3) were incubated with CaMKII delta monoclonal antibody (Product # MA570445) at a dilution of 1:5,000, followed by HRP-conjugated goat anti-rabbit secondary antibody (1:20,000) respectively. Image was developed using NaQECL Substrate Kit.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA570446
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293F
Class
Recombinant Monoclonal
Type
Antibody
Clone
25GB605
Immunogen
A synthesized peptide derived from human (3-54) CaMKII delta.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Dry ice (international)
Target Information
CaMKII delta belongs to the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. is a delta chain. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Distinct isoforms of this chain have different expression patterns.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Ca++/calmodulin-dependent protein kinase 2 delta subunit; Ca++/calmodulin-dependent protein kinase II delta subunit; Ca++/calmodulin-dependent protein kinase II, delta subunit; calcium/calmodulin-dependent protein kinase (CaM kinase) II delta; calcium/calmodulin-dependent protein kinase type II delta chain; Calcium/calmodulin-dependent protein kinase type II subunit delta; CaM kinase II subunit delta; caM-kinase II delta chain; CAM2; caMK-II subunit delta; CAMK2B; CAMK2G; CAMKB; CAMKG
Gene Aliases: 2810011D23Rik; 8030469K03Rik; [d]-CaMKII; CaMK II; CAMK1; Camk2; CAMK2D; CAMKD; Camki; Kiaa4163; RATCAMKI
UniProt ID: (Rat) P15791, (Mouse) Q6PHZ2
Entrez Gene ID: (Rat) 24246, (Mouse) 108058
protein serine/threonine kinase activity
calmodulin-dependent protein kinase activity
protein binding
calmodulin binding
ATP binding
sodium channel inhibitor activity
titin binding
protein homodimerization activity
ion channel binding
nitric-oxide synthase binding
nucleotide binding
protein kinase activity
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
non-receptor serine/threonine protein kinase
G1/S transition of mitotic cell cycle
response to hypoxia
regulation of sodium ion transport
regulation of membrane depolarization
protein phosphorylation
calcium ion transport
regulation of G2/M transition of mitotic cell cycle
positive regulation of cardiac muscle hypertrophy
regulation of cell communication by electrical coupling
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
positive regulation of smooth muscle cell migration
peptidyl-serine phosphorylation
peptidyl-threonine phosphorylation
cellular potassium ion homeostasis
endoplasmic reticulum calcium ion homeostasis
positive regulation of Rac protein signal transduction
protein autophosphorylation
positive regulation of smooth muscle cell proliferation
protein oligomerization
relaxation of cardiac muscle
cardiac muscle contraction
regulation of cellular localization
cell growth involved in cardiac muscle cell development
positive regulation of ERK1 and ERK2 cascade
cardiac muscle cell contraction
regulation of cardiac muscle cell action potential
regulation of cardiac muscle cell action potential involved in regulation of contraction
regulation of cell communication by electrical coupling involved in cardiac conduction
regulation of relaxation of cardiac muscle
negative regulation of sodium ion transmembrane transport
regulation of calcium ion transmembrane transport via high voltage-gated calcium channel
negative regulation of sodium ion transmembrane transporter activity
phosphorylation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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