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Invitrogen
NME3 Recombinant Rabbit Monoclonal Antibody (25GB4105)
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FIGURE: 1 / 4
NME3 Antibody (MA570764) in ICC/IF
Immunocytochemistry analysis of NME3 in HepG2 cells. Sample was incubated with NME3 monoclonal antibody (Product # MA570763) at a dilution of 1:1,000. Nuclei were stained blue with DAPI and Alexa Fluor 647. Images were taken using Leica stellaris 5. Protein abundance based on laser Intensity and smart gain: Medium. Scale bar, 20 μm.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA570764
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293F
Class
Recombinant Monoclonal
Type
Antibody
Clone
25GB4105
Immunogen
A synthesized peptide derived from human (61-74) NME3.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.9 mg/mL
Amount
18 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Dry ice (international)
Target Information
NME3 mRNA is preferentially expressed at early stages of myeloid differentiation of highly purified CD34(+) cells. Its constitutive expression in a myeloid precursor line, which is growth-factor dependent for both proliferation and differentiation, results in inhibition of granulocytic differentiation induced by granulocyte colony-stimulating factor and causes apoptotic cell death. These results appear consistent with a role for the NME3 gene in normal hematopoiesis and raise the possibility that its overexpression contributes to differentiation arrest, a feature of blastic transformation in chronic myelogenous leukemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DR-nm23; expressed in non-metastatic cells 3; expressed in non-metastatic cells 3 protein (nucleoside diphosphate kinase); expressed in non-metastatic cells 3, protein (nucleoside diphosphate kinase); NDK 3; NDK3; NDP kinase 3; NDPK-C; NDPKC; nm23-H3; nm23-M3; non-metastatic cell expressed protein 3; non-metastatic cells 3, protein expressed in; Nucleoside diphosphate kinase 3; Nucleoside diphosphate kinase C; nucleoside diphosphate kinase DR-nm23
Gene Aliases: 1810009F08Rik; AI413736; DR-nm23; Ndk3; NM23-dr; Nm23-M3; NME3
UniProt ID: (Mouse) Q9WV85
Entrez Gene ID: (Rat) 85269, (Mouse) 79059
purine nucleotide metabolic process
nucleoside diphosphate phosphorylation
GTP biosynthetic process
pyrimidine nucleotide metabolic process
UTP biosynthetic process
CTP biosynthetic process
biological_process
nucleoside triphosphate biosynthetic process
regulation of apoptotic process
nucleotide metabolic process
phosphorylation
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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