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Invitrogen
IQGAP1 Recombinant Rabbit Monoclonal Antibody (25GB1900)
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图: 1 / 4
IQGAP1 Antibody (MA570878) in ICC/IF
Immunocytochemistry analysis of IQGAP1 in C2C12 cells. Sample was incubated with IQGAP1 monoclonal antibody (Product # MA570877) at a dilution of 1:1,000. Nuclei were stained blue with DAPI and Alexa Fluor 647. Images were taken using Leica stellaris 5. Protein abundance based on laser Intensity and smart gain: Medium. Scale bar, 20 μm.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA570878
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293F
分类
Recombinant Monoclonal
类型
Antibody
克隆号
25GB1900
抗原
A synthesized peptide derived from human (1-1657) IQGAP1.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Dry ice (international)
靶标信息
This gene encodes a member of the IQGAP family. The protein contains four IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. Expression of the protein is upregulated by gene amplification in two gastric cancer cell lines.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Cdc42-Rac1 effector protein; DISP2; DISPB; p195; Ras GTPase-activating-like protein IQGAP1
基因别名: AA682088; D7Ertd237e; D7Ertd257e; IQGAP1; KIAA0051; mKIAA0051
UniProt ID: (Mouse) Q9JKF1
Entrez Gene ID: (Mouse) 29875, (Rat) 361598
GTPase activator activity
protein binding
calmodulin binding
phosphatidylinositol-3,4,5-trisphosphate binding
Rho GTPase binding
protein kinase binding
protein phosphatase binding
protein complex binding
protein serine/threonine kinase activator activity
Rac GTPase binding
G-protein modulator
protein-binding activity modulator
GTPase-activating protein
regulation of cytokine production
signal transduction
epidermal growth factor receptor signaling pathway
small GTPase mediated signal transduction
fibroblast growth factor receptor signaling pathway
negative regulation of dephosphorylation
cellular response to platelet-derived growth factor stimulus
regulation of GTPase activity
cellular response to fibroblast growth factor stimulus
positive regulation of protein kinase activity
platelet-derived growth factor receptor signaling pathway
cellular response to calcium ion
cellular response to epidermal growth factor stimulus
positive regulation of protein serine/threonine kinase activity
neuron projection extension
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
