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Invitrogen
CHMP5 Monoclonal Antibody (24GB8030)
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CHMP5 Antibody (MA571189) in WB
Western blot analysis of CHMP5. Samples (HT-1080, HepG2, HeLa, HAP-1, H9C2, C2C12) were incubated with CHMP5 monoclonal antibody (Product # MA571189) at a dilution of 1:1,000, followed by HRP-conjugated goat anti-mouse secondary antibody (1:20,000) respectively. Image was developed using NaQECL Substrate Kit.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA571189
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
24GB8030
抗原
Recombinant protein of human (1-219) CHMP5.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Dry ice (international)
靶标信息
CHMP5 belongs to the chromatin-modifying protein/charged multivesicular body protein family. These proteins are components of ESCRT-III, a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies. Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A, is required for both MVB formation and regulation of cell cycle progression.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Charged multivesicular body protein 5; chromatin modifying protein 5; Chromatin-modifying protein 5; HGNC:26942; likely ortholog of H. sapiens SNF7 domain containing 2; SNF7 domain-containing protein 2; Vacuolar protein sorting-associated protein 60; Vps60
基因别名: 2210412K09Rik; AW545668; C9orf83; CGI-34; CHMP5; HSPC177; PNAS-114; PNAS-2; RGD1305968; SNF7DC2
UniProt ID: (Mouse) Q9D7S9, (Rat) Q5RK31
Entrez Gene ID: (Mouse) 76959, (Rat) 297995
cell separation after cytokinesis
regulation of receptor recycling
transport
nucleus organization
vacuolar transport
lysosome organization
mitotic metaphase plate congression
endosome to lysosome transport
regulation of centrosome duplication
protein transport
viral budding
multivesicular body sorting pathway
regulation of mitotic spindle assembly
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