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Invitrogen
BCAT1 Monoclonal Antibody (24GB7945)
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图: 1 / 6
BCAT1 Antibody (MA571279) in ICC/IF
Immunocytochemistry analysis of BCAT1 in HeLa cells. Sample was incubated with BCAT1 monoclonal antibody (Product # MA571279) at a dilution of 1:1,000. Top panel: wild-type (WT); Bottom panel: BCAT1 shRNA knockdown (KD). Nuclei were stained blue with DAPI and Alexa Fluor 647. Scale bar, 20 μm.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA571279
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
宿主/亚型
Mouse
/ IgG2a
分类
Monoclonal
类型
Antibody
克隆号
24GB7945
抗原
Recombinant protein of human (1-386) BCAT1.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Dry ice (international)
靶标信息
This gene encodes the cytosolic form of the enzyme branched-chain amino acid transaminase. This enzyme catalyzes the reversible transamination of branched-chain alpha-keto acids to branched-chain L-amino acids essential for cell growth. Two different clinical disorders have been attributed to a defect of branched-chain amino acid transamination: hypervalinemia and hyperleucine-isoleucinemia. As there is also a gene encoding a mitochondrial form of this enzyme, mutations in either gene may contribute to these disorders. Alternatively spliced transcript variants have been described.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: BCAT(c); branched chain amino-acid transaminase 1, cytosolic; branched chain aminotransferase 1, cytosolic; Branched-chain-amino-acid aminotransferase, cytosolic; ECA39; placental protein 18; unnamed protein product
基因别名: BCAT1; BCATC; BCT1; ECA39; MECA39; PNAS121; PP18
UniProt ID: (Mouse) P24288
Entrez Gene ID: (Human) 586, (Mouse) 12035
catalytic activity
branched-chain-amino-acid transaminase activity
protein binding
L-leucine transaminase activity
L-valine transaminase activity
L-isoleucine transaminase activity
transaminase activity
transferase activity
identical protein binding
transaminase
transferase
metabolite interconversion enzyme
G1/S transition of mitotic cell cycle
isoleucine catabolic process
leucine catabolic process
valine catabolic process
branched-chain amino acid metabolic process
branched-chain amino acid biosynthetic process
metabolic process
cellular amino acid biosynthetic process
branched-chain amino acid catabolic process
mitotic G1 DNA damage checkpoint
cellular response to UV
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
