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Invitrogen
CaV2.3 Recombinant Rabbit Monoclonal Antibody (PSH13-51)
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图: 1 / 9
CaV2.3 Antibody (MA571370) in IHC (P)
Immunohistochemical analysis of CaV2.3 on formalin-fixed paraffin-embedded mouse kidney (negative) tissue. The section was pre-treated using heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0) for 20 minutes. The tissue was blocked in 1% BSA for 20 minutes at room temperature, then probed with CaV2.3 Recombinant Rabbit Monoclonal Antibody (PSH13-51) (Product # MA571370) at 1:3,000 dilution for 1 ... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA571370
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
PSH13-51
抗原
Recombinant protein within human CACNA1E aa 1,964-2,313.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
PBS, pH 7.4, with 0.1% BSA, 40% glycerol
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Positive Control: Mouse striatum tissue, mouse hippocampus tissue, rat hippocampus tissue, Mouse brain tissue lysate, Mouse hippocampus tissue lysate, Rat brain tissue lysate
Tissue Specificity: Tissue enriched (brain)
Subcellular Location: Membrane.
Sequence Similarities: 95% Mouse/Rat
Predicted band size: 262 kDa.
靶标信息
The expression of multiple classes of voltage dependent calcium channels (VDCCs) allows neurons to tailor calcium signaling to functionally discrete cellular regions. Although N-Type VDCCs exist before birth which is consistent with a role in migration, most N-Type VDCCs subunit expression is postnatal and is important in the genesis of synaptic transmission in discrete hippocampal fields.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: BII; Brain calcium channel II; Calcium channel, L type, alpha-1 polypeptide, isoform 6; calcium channel, voltage-dependent, L type, alpha 1E subunit; RBE-II; RBE2; voltage gated calcium channel alpha1E subunit; voltage-dependent calcium channel alpha1-E subunit; Voltage-dependent R-type calcium channel subunit alpha-1E; Voltage-gated calcium channel subunit alpha Cav2.3
基因别名: A430040I15; alpha1E; BII; CACH6; CACHA1E; CACNA1E; CACNL1A6; Cav2.3; Cchra1
Entrez Gene ID: (Rat) 54234, (Mouse) 12290
behavioral fear response
regulation of heart rate
calcium ion transport
chemical synaptic transmission
locomotory behavior
visual learning
transmission of nerve impulse
sensory perception of pain
sperm motility
regulation of ion transmembrane transport
glucose homeostasis
fear response
response to pain
behavioral response to pain
neurological system process
regulation of insulin secretion involved in cellular response to glucose stimulus
calcium ion import
calcium ion transmembrane transport
membrane depolarization during action potential
regulation of somatostatin secretion
transport
ion transport
transmembrane transport
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
