Search
Invitrogen
Decorin Recombinant Rabbit Monoclonal Antibody (PSH12-99)
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
图: 1 / 21
Decorin Antibody (MA571377) in IHC (P)
Immunohistochemical analysis of Decorin was performed using formalin-fixed paraffin-embedded mouse ovary and mouse brain tissue sections. To expose the target protein, heat-induced epitope retrieval was performed on de-paraffinized sections using eBioscience™ IHC Antigen Retrieval Solution - High pH (10X) (Product # 00-4956-58) diluted to 1X solution in water in a decloaking chamber at 110°C for 15 min. The... View More
产品信息
MA571377
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
PSH12-99
抗原
Recombinant protein within human Decorin aa 1-359.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
PBS, pH 7.4, with 0.1% BSA, 40% glycerol
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Positive Control: Mouse colon tissue lysate, Rat kidney tissue lysate, Rat colon tissue lysate, Rat placenta tissue lysate, human heart tissue, human kidney tissue, mouse heart tissue, mouse kidney tissue, rat heart tissue, rat kidney tissue.
Tissue Specificity: Tissue enhanced (ovary)
Subcellular Location: Secreted, extracellular space, extracellular matrix.
Sequence Similarities: 78% Mouse/Rat
Predicted band size: 40 kDa
靶标信息
Decorin is a member of the small, leucine-rich proteoglycan (SLRP) family along with biglycan. Found in the interterritorial region of cartilage, decorin interacts with collagen and other matrix proteins to regulate the cartilaginous matrix. It has been shown to interact with fibronectin, thrombospondin, C1q, epidermal growth factor receptor (EGFR), and TGF-b. It is believed that decorin also plays a role in the cell cycle of chondrocytes. The decorin neoepitope fragment has a sequence of PKTLQE, and is generated by MMP-3 or ADAMTS-4 cleavage at Glu154-Leu155 of decorin core protein.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: Bone proteoglycan II; DCN; Decorin; Dermatan sulfate proteoglycan-II; dermatan sulfate proteoglycan-II (decorin); dermatan sulphate proteoglycans II; Dermatan sulphate proteoglycans II (DSPG2); DSPG; PG-S2; PG40; proteoglycan core protein; Small leucine rich protein 1B; small leucine-rich protein 1B; unnamed protein product
基因别名: CSCD; DC; DCN; DSPG2; mDcn; PG40; PGII; PGS2; SLRR1B
UniProt ID: (Human) P07585, (Mouse) P28654, (Rat) Q01129
Entrez Gene ID: (Human) 1634, (Mouse) 13179, (Rat) 29139
positive regulation of autophagy
peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan
kidney development
placenta development
skeletal muscle tissue development
aging
response to mechanical stimulus
response to lipopolysaccharide
wound healing
organ morphogenesis
negative regulation of endothelial cell migration
positive regulation of macroautophagy
negative regulation of angiogenesis
positive regulation of transcription from RNA polymerase II promoter
positive regulation of protein kinase B signaling
positive regulation of mitochondrial depolarization
positive regulation of mitochondrial fission
negative regulation of vascular endothelial growth factor signaling pathway
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
