Invitrogen

CD105 Monoclonal Antibody (SN6)

1个已发表图片

6 篇参考文献

查看其他88个CD105 (Endoglin)抗体

问题与答案

问题与答案

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CD105 Antibody in Immunocytochemistry, Flow Cytometry (ICC/IF, Flow)

CD105 Antibody in Immunocytochemistry, Flow Cytometry (ICC/IF, Flow)

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CD105 Antibody (MHCD10500) in ICC/IF, Flow

PloS one 2016 - Published figure using CD105 monoclonal antibody (Product # MHCD10500) in Immunocytochemistry and Flow Cytometry

CD105 Antibody in Immunocytochemistry, Flow Cytometry (ICC/IF, Flow)

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CD105 Antibody in Immunocytochemistry, Flow Cytometry (ICC/IF, Flow) — Published figure using CD105 monoclonal antibody (Product # MHCD10500) in Immunocytochemistry and Flow Cytometry

产品信息

MHCD10500

应用

建议稀释比

已发表文章

免疫组化 (IHC)

-

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免疫细胞化学 (ICC/IF)

-

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流式细胞分析 (Flow)

Assay-Dependent

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产品规格

种属反应

Human

已发表种属

Cat, Human, Sheep

宿主/亚型

Mouse / IgG1

分类

Monoclonal

类型

Antibody

克隆号

SN6

抗原

Human CD105 (Endoglin)

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

纯化类型

purified

保存液

PBS

内含物

0.1% sodium azide

保存条件

4°C, store in dark

运输条件

Ambient (domestic); Wet ice (international)

靶标信息

CD105 or Endoglin is a Type I transmembrane protein, which is highly expressed on human vascular endothelial cells. It exists on an O- and N-glycosylated homodimer. Up regulation of endoglin expression has been demonstrated in tumor vasculature and proliferating cells, suggesting that it is a proliferation associated endothelial marker. CD105 binds to TGF beta 1 and 3 with high affinity but not to TGF beta 2.

Analyte Specific Reagent

生物信息学

蛋白别名: CD105; CD105 antigen; Endoglin; ORW

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基因别名: END; ENG; HHT1; ORW1

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UniProt ID: (Human) P17813

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Entrez Gene ID: (Human) 2022

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transmembrane signaling receptor activity transforming growth factor beta receptor, cytoplasmic mediator activity type II transforming growth factor beta receptor binding protein binding galactose binding glycosaminoglycan binding type I transforming growth factor beta receptor binding BMP binding protein homodimerization activity activin binding transforming growth factor beta binding transmembrane signal receptor

chronological cell aging patterning of blood vessels vasculogenesis positive regulation of protein phosphorylation heart looping sprouting angiogenesis endocardial cushion morphogenesis cardiac ventricle morphogenesis cardiac atrium morphogenesis ventricular trabecula myocardium morphogenesis cell migration involved in endocardial cushion formation regulation of transcription, DNA-templated cell adhesion negative regulation of gene expression positive regulation of pathway-restricted SMAD protein phosphorylation regulation of transforming growth factor beta receptor signaling pathway central nervous system vasculogenesis negative regulation of cell migration BMP signaling pathway positive regulation of BMP signaling pathway negative regulation of protein autophosphorylation dorsal aorta morphogenesis positive regulation of angiogenesis positive regulation of transcription from RNA polymerase II promoter smooth muscle tissue development artery morphogenesis venous blood vessel morphogenesis endocardial cushion to mesenchymal transition positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation