Zinc-buffering capacity of a eukaryotic cell at physiological pZn.
AuthorsKrezel A, Maret W
JournalJ Biol Inorg Chem
PubMed ID16924557
In spite of the paramount importance of zinc in biology, dynamic aspects of cellular zinc metabolism remain poorly defined at the molecular level. Investigations with human colon cancer (HT-29) cells establish a total cellular zinc concentration of 264 microM. Remarkably, about 10% of the potential high-affinity zinc-binding sites are not ... More