NuPAGE™ 4 to 12%, Bis-Tris, 1.0 mm, Mini Protein Gel, 2D-well, 10 gels (1 box) - Citations
NuPAGE™ 4 to 12%, Bis-Tris, 1.0 mm, Mini Protein Gel, 2D-well, 10 gels (1 box) - Citations
View additional product information for NuPAGE™ Bis-Tris Mini Protein Gels, 4–12%, 1.0–1.5 mm - Citations (NP0335PK2, NP0322BOX, NP0327BOX, NP0321BOX, NP0326BOX, NP0330BOX, NP0323BOX, NP0324BOX, NP0329PK2, NP0322PK2, NP0321PK2, NP0336BOX, NP0323PK2, NP0335BOX, NP0329BOX, NP0336PK2)
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Citations & References
Abstract
Hsp27 regulates Akt activation and polymorphonuclear leukocyte apoptosis by scaffolding MK2 to Akt signal complex.
AuthorsWu R, Kausar H, Johnson P, Montoya-Durango DE, Merchant M, Rane MJ,
JournalJ Biol Chem
PubMed ID17510053
We have shown previously that Akt exists in a signal complex with p38 MAPK, MAPK-activated protein kinase-2 (MK2), and heat shock protein 27 (Hsp27) and MK2 phosphorylates Akt on Ser-473. Additionally, dissociation of Hsp27 from Akt, prior to Akt activation, induced polymorphonuclear leukocyte (PMN) apoptosis. However, the role of Hsp27 ... More