Cluster analysis of mass spectrometry data reveals a novel component of SAGA.
AuthorsPowell DW, Weaver CM, Jennings JL, McAfee KJ, He Y, Weil PA, Link AJ,
JournalMol Cell Biol
PubMed ID15282323
The SAGA histone acetyltransferase and TFIID complexes play key roles in eukaryotic transcription. Using hierarchical cluster analysis of mass spectrometry data to identify proteins that copurify with components of the budding yeast TFIID transcription complex, we discovered that an uncharacterized protein corresponding to the YPL047W open reading frame significantly associated ... More