Validated assays for human cytochrome P450 activities.
AuthorsWalsky RL, Obach RS,
JournalDrug Metab Dispos
PubMed ID15155557
'The measurement of the effect of new chemical entities on human cytochrome P450 marker activities using in vitro experimentation represents an important experimental approach in drug development. In vitro drug interaction data can be used in guiding the design of clinical drug interaction studies, or, when no effect is observed ... More