A novel fluorescent tracer for visualizing coupled cells in neural circuits of living tissue.
AuthorsHoshi H, O'Brien J, Mills SL
JournalJ Histochem Cytochem
PubMed ID16864895
'Gap junctions have diverse roles in a wide variety of tissues and have recently become a subject of intense investigation in neural circuits where synchrony and oscillations may play an important part. In circuits where gap junctions are present, the possibility arises of identifying intercommunicating cells via introduction of tracer ... More
Role of poly(ADP-ribosyl)ation in DNA-PKcs- independent V(D)J recombination.
AuthorsBrown ML, Franco D, Burkle A, Chang Y
JournalProc Natl Acad Sci U S A
PubMed ID11930007
V(D)J recombination is critical to the generation of a functional immune system. Intrinsic to the assembly of antigen receptor genes is the formation of endogenous DNA double-strand breaks, which normally are excluded from the cellular surveillance machinery because of their sequestration in a synaptic complex and/or rapid resolution. In cells ... More
Molecular dissection of the Rho-associated protein kinase (p160ROCK)-regulated neurite remodeling in neuroblastoma N1E-115 cells.
AuthorsHirose M, Ishizaki T, Watanabe N, Uehata M, Kranenburg O, Moolenaar WH, Matsumura F, Maekawa M, Bito H, Narumiya S
JournalJ Cell Biol
PubMed ID9647654
A critical role for the small GTPase Rho and one of its targets, p160ROCK (a Rho-associated coiled coil-forming protein kinase), in neurite remodeling was examined in neuroblastoma N1E-115 cells. Using wild-type and a dominant-negative form of p160ROCK and a p160ROCK-specific inhibitor, Y-27632, we show here that p160ROCK activation is necessary ... More
Serial Measurements of Apoptotic Cell Numbers Provide Better Acceptance Criterion for PBMC Quality than a Single Measurement Prior to the T Cell Assay.
Authors
JournalCells
PubMed ID25585298
Isolation of cell type-specific apoptotic bodies by fluorescence-activated cell sorting.
Authors
JournalSci Rep
PubMed ID28057919
Interconnections between apoptotic and autophagic pathways during thiopurine-induced toxicity in cancer cells: the role of reactive oxygen species.