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Invitrogen
SLC7A11 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA1-16775
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide made to a region within the N-terminus of the mouse xCT protein (between residues 1-50).
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This antibody is predicted to react with mouse and canine based on 100% sequence homology.
This antibody has 94% sequence homology with rat.
Suggested positive control: human stomach protein, stomach tissue lysate.
Immunogen sequence homology: orangutan (82%).
靶标信息
SLC7A11 (also known as XCT) is a member of a hetromeric, sodium-independent, anionic amino acid transport system. It is highly specific for cysteine and glutamate. SLC7A11 is a mediator of Kaposi sarcoma-associated herpes virus fusion and entry into cells. Increased expression of this protein in primary gliomas is associated with neuronal cell death.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Amino acid transport system xc-; Calcium channel blocker resistance protein CCBR1; cysteine/glutamate transporter; Cystine/glutamate transporter; sodium independent anionic amino acid transport system; solute carrier family 7 (cationic amino acid transporter, y+ system), member 11; Solute carrier family 7 member 11; Subtle gray protein; xCT
基因别名: 9930009M05Rik; AI451155; SLC7A11; sut; xCT
UniProt ID: (Mouse) Q9WTR6
Entrez Gene ID: (Mouse) 26570, (Rat) 310392
amino acid transmembrane transport
transport
amino acid transport
response to toxic substance
neutral amino acid transport
platelet aggregation
modified amino acid transport
L-glutamate transmembrane transport
response to oxidative stress
brain development
response to nicotine
lens fiber cell differentiation
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