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Invitrogen
Kinesin 5B Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA1-19392
产品规格
种属反应
Human,
Mouse,
Pig
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Stalk domain of human kinesin, expressed in (aa 331-906) E. coli.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4
内含物
15mM sodium azide
保存条件
4°C, do not freeze
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This antibody detects total level of endogenous kinesin protein (intracellular antigen).
靶标信息
Microtubule-dependent motor required for normal distribution of mitochondria and lysosomes. Can induce formation of neurite-like membrane protrusions in non-neuronal cells in a ZFYVE27-dependent manner. Regulates centrosome and nuclear positioning during mitotic entry. During the G2 phase of the cell cycle in a BICD2-dependent manner, antagonizes dynein function and drives the separation of nuclei and centrosomes. Required for anterograde axonal transportation of MAPK8IP3/JIP3 which is essential for MAPK8IP3/JIP3 function in axon elongation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Conventional kinesin heavy chain; kinesin heavy chain member 5B, ubiquitous; Kinesin-1 heavy chain; U-KHC; Ubiquitous kinesin heavy chain; UKHC
基因别名: AL022807; Khc; Khcs; KIF5B; KNS; KNS1; Ukhc
UniProt ID: (Mouse) Q61768
Entrez Gene ID: (Pig) 595132, (Mouse) 16573
mitochondrial transport
microtubule-based process
microtubule-based movement
cytoplasm organization
axon guidance
protein localization
metabolic process
positive regulation of synaptic transmission, GABAergic
stress granule disassembly
regulation of membrane potential
positive regulation of potassium ion transport
vesicle transport along microtubule
plus-end-directed vesicle transport along microtubule
positive regulation of establishment of protein localization to plasma membrane
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