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PA1-25353 detects MCM2 (phospho S41) from human samples.
PA1-25353 has been successfully used in Western blot procedures.
The PA1-25353 immunogen is a synthetic phosphorylated peptide corresponding to a portion of human MCM2 surrounding Serine41 (LocusLink ID 4171).
MCM2 (Mini chromosome maintenance protein 2) is involved in regulating DNA replication. MCM2 (also called CDCL1, mitotin and BM28), is a human nuclear protein that is crucial in the cell cycle, being involved in the onset of DNA replication and cell division. It is similar to members of the family of early S-phase proteins. MCM2 has been mapped to 3q21. From its localization, CDCL1 became a candidate for an oncogene affected by chromosomal breaks in acute myeloid leukemia (AML).
仅用于科研。不用于诊断过程。未经明确授权不得转售。