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Invitrogen
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PA1-27579 detects NBR2 from human samples.
PA1-27579 may be successfully used in Western blot applications.
The immunogen is a synthetic peptide corresponding to human Protein NBR2.
This gene was identified by its close proximity on chromosome 17 to tumor suppressor gene BRCA1. Experimental evidence indicates that the two genes share a bi-directional promoter. Transcription for either gene is controlled individually by distinct transcriptional repressor factors. A short (112 amino acid) open reading frame is observed which includes a region derived from a LINE1 element. A strong Kozak signal is not observed for the putative ORF and the stop codon is more than 55 bases upstream of the last splice site for the transcript suggesting that the transcript is subject to nonsense-mediated decay. Therefore, this gene does not appear to encode a protein.
仅用于科研。不用于诊断过程。未经明确授权不得转售。