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Invitrogen
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PA1-27754 detects EIF3S4 from human, mouse, and rat samples.
PA1-27754 may be successfully used in Western blot applications.
The PA1-27537 immunogen is a synthetic peptide corresponding to human Eukaryotic translation initiation factor 3 subunit 4.
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. This subunit can bind 18S rRNA.
仅用于科研。不用于诊断过程。未经明确授权不得转售。