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Invitrogen
Collagen III Polyclonal Antibody
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Collagen III Antibody (PA1-28870) in IHC (P)
Immunohistochemistry analysis of Collagen III was performed in human skin and testis tissue using Collagen III Polyclonal Antibody (Product # PA1-28870) at a dilution of 1:400 for 45 minutes a room temperature. The antibody showed strong staining in FFPE sections of human skin (left, dermis) with moderate to strong red staining and testis (right) where strong staining was observed within connective tissue b... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA1-28870
应用
建议稀释比
已发表文章
产品规格
种属反应
Bovine,
Human,
Mouse,
Pig
已发表种属
Human,
Pig,
Rhesus monkey
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Collagen Type III from human and bovine placenta.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1.16 mg/mL
规格
100 µg
纯化类型
Antigen affinity chromatography
保存液
20mM potassium phosphate, pH 7.2, with 150mM NaCl
内含物
0.01% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
PA1-28870 has been successfully used in ELISA, immunohistochemistry (frozen tissue), immunoprecipitation, and Western blot applications. NOTE: The preparation of a specific antibody to Collagen III's uninterrupted "Glycine-X-Y" triplet repeat requires a non-denatured epitope format. Consequently, it is recommended to use this antibody in a Western blot using non-denaturing or "native" conditions.
Store as concentrated solution. Centrifuge briefly prior to opening vial.
靶标信息
Collagen III is a fibrillar collagen that is found in extensible connective tissues such as skin, lung, and the vascular system, frequently in association with type I Collagen. Mutations in th gene are associated with Ehlers Danlos syndrome type IV, and with aortic and arterial aneurysms. Although alternate transcripts have been detected for this gene, they are the result of mutations; these mutations alter splicing, often leading to the exclusion of multiple exons.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: COL 3; COL3; COL3 alpha 1; Collagen 3; Collagen alpha-1(III) chain; collagen, type III, alpha 1 (Ehlers-Danlos syndrome type IV, autosomal dominant); collagen, type III, alpha 1 chain, fibril forming; Collagen3; FLJ34534; MGC93704; minisatellite 10w detected by probe MMS10; procollagen, type III, alpha 1; type III collagen
基因别名: AW550625; Col3a-1; COL3A1; mKIAA4231; MMS10-W; Ms10w
UniProt ID: (Mouse) P08121
Entrez Gene ID: (Bovine) 510833, (Pig) 100152001, (Mouse) 12825
cerebral cortex development
positive regulation of Rho protein signal transduction
negative regulation of neuron migration
blood vessel development
cell-matrix adhesion
transforming growth factor beta receptor signaling pathway
integrin-mediated signaling pathway
heart development
response to radiation
peptide cross-linking
collagen fibril organization
response to cytokine
wound healing
extracellular fibril organization
skin development
digestive tract development
negative regulation of immune response
aorta smooth muscle tissue morphogenesis
cellular response to amino acid stimulus
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
