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Invitrogen
Beclin 1 Polyclonal Antibody
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产品信息
PA1-31312
应用
建议稀释比
已发表文章
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide (Human) (Internal sequence within residues 1-100).
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
产品详细信息
PA1-31312 detects Beclin 1 from human samples. Expected to cross-react with mouse and rat due to 94% and 88% sequence homology.
PA1-31312 has been successfully used in immunoprecipitation and Western blot applications.
The PA1-31312 immunogen is synthetic peptide (Human) (Internal sequence within residues 1-100).
Store at 4°C short term. For extended storage aliquot and store at -20°C or below. Avoid freeze/thaw cycles.
靶标信息
Beclin 1 plays a central role in autophagy. It acts as a core subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate. Different PI3K complex forms are believed to play a role in multiple membrane trafficking pathways - PI3KC3-C1 is involved in the initation of autophagosomes and PI3KC3-C2 is involved in the maturation of autophagosomes and endocytosis. Beclin 1 also plays a role in antiviral host defense.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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