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Invitrogen
Caspase 4 Polyclonal Antibody
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产品信息
PA1-32038
产品规格
宿主/亚型
Chicken
/ IgY
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide, corresponding to amino acids 1-89 of Human Caspase 4.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
规格
50 µg
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
PA1-32038 detects Caspase 4 from human samples.
PA1-32038 has been successfully used in Western blot applications.
The PA1-32038 immunogen is: Synthetic peptide, corresponding to amino acids 1-89 of Human Caspase 4.
靶标信息
This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This caspase is able to cleave and activate its own precursor protein, as well as caspase 1 precursor. When overexpressed, this gene induces cell apoptosis. Alternative splicing results in transcript variants encoding distinct isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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