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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
With DHDDS, forms the dehydrodolichyl diphosphate synthase (DDS) complex, an essential component of the dolichol monophosphate (Dol-P) biosynthetic machinery. Adds multiple copies of isopentenyl pyrophosphate (IPP) to farnesyl pyrophosphate (FPP) to produce dehydrodolichyl diphosphate (Dedol-PP), a precursor of dolichol which is utilized as a sugar carrier in protein glycosylation in the endoplasmic reticulum (ER). Regulates the glycosylation and stability of nascent NPC2, thereby promoting trafficking of LDL-derived cholesterol. Acts as a specific receptor for the N-terminus of Nogo-B, a neural and cardiovascular regulator.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Cis-prenyltransferase subunit NgBR; dehydrodolichyl diphosphate syntase complex subunit Nus1; Dehydrodolichyl diphosphate synthase complex subunit NUS1; di-trans,poly-cis-decaprenylcistransferase; NgBR; Nogo-B receptor; Nuclear undecaprenyl pyrophosphate synthase 1 homolog
基因别名: 1600027K07Rik; AU019165; AW538011; BC003223; C6orf68; D10Ertd438e; NGBR; NUS1; RGD1307879
UniProt ID: (Mouse) Q99LJ8
Entrez Gene ID: (Rat) 294400, (Mouse) 52014