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Invitrogen
NUS1 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA1-41202
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to amino acids 64-74 of human Nogo-B receptor (NgBR).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1.0 mg/mL
Amount
100 µg
Purification
Protein G
Storage buffer
PBS
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
With DHDDS, forms the dehydrodolichyl diphosphate synthase (DDS) complex, an essential component of the dolichol monophosphate (Dol-P) biosynthetic machinery. Adds multiple copies of isopentenyl pyrophosphate (IPP) to farnesyl pyrophosphate (FPP) to produce dehydrodolichyl diphosphate (Dedol-PP), a precursor of dolichol which is utilized as a sugar carrier in protein glycosylation in the endoplasmic reticulum (ER). Regulates the glycosylation and stability of nascent NPC2, thereby promoting trafficking of LDL-derived cholesterol. Acts as a specific receptor for the N-terminus of Nogo-B, a neural and cardiovascular regulator.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: cis-prenyltransferase subunit NgBR; dehydrodolichyl diphosphate syntase complex subunit NUS1; di-trans,poly-cis-decaprenylcistransferase; ngBR; Nogo-B receptor; nuclear undecaprenyl pyrophosphate synthase 1 homolog; transport and golgi organization 14 homolog; unnamed protein product
Gene Aliases: 1600027K07Rik; C6orf68; CDG1AA; D10Ertd438e; MGC:7199; MRD55; NgBR; RGD1307879; TANGO14
UniProt ID: (Human) Q96E22, (Mouse) Q99LJ8
Entrez Gene ID: (Human) 116150, (Mouse) 52014, (Rat) 294400
dolichyl diphosphate biosynthetic process
glycoprotein biosynthetic process
regulation of intracellular cholesterol transport
protein O-linked mannosylation
vascular endothelial growth factor signaling pathway
cholesterol homeostasis
dolichyl monophosphate biosynthetic process
sterol homeostasis
positive regulation of cell migration involved in sprouting angiogenesis
positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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