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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
PA1-4264 detects CLAN protein from human samples. This antibody detects both A and B isoforms.
PA1-4264 has been successfully used in Western blot procedures. By Western blot this antibody detects a ~116 kDa protein representing CLAN-A and a ~43 kDa protein representing CLAN-B in lung lysate.
PA1-4264 immunizing peptide corresponds to N-terminal sequence M N F I K D N S R A L I Q R M G M.
NLRC4 encodes a member of the caspase recruitment domain-containing NLR family. Family members play essential roles in innate immune response to a wide range of pathogenic organisms, tissue damage and other cellular stresses. Mutations in this gene result in autoinflammation with infantile enterocolitis. Alternative splicing results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: CARD, LRR, and NACHT-containing protein; Caspase recruitment domain-containing protein 12; CED-4-like protein Clan; Ice protease-activating factor; Ipaf; NLR family CARD domain-containing protein 4
基因别名: CARD12; CLAN; CLAN1; IPAF; NLRC4; UNQ6189/PRO20215
Entrez Gene ID: (Human) 58484